141 -5 (67) 2024 - Kholboeva G.B. - MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN THE LIVER IN CEREBRAL ISCHEMIC STROKE

MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN THE LIVER IN CEREBRAL ISCHEMIC STROKE

Kholboeva G.B. - Ministry of Health of the Republic of Uzbekistan, Urgent medical care city clinical hospital of Uzbekistan

Resume

The article describes morphological and biochemical changes in the liver in acute cerebrovascular accidents. It is known that situations that disrupt hepatic blood flow include all damaging factors that negatively affect liver function. These factors include most of the medications in the modern arsenal and also a damaged liver, which in itself can change the course of many pathological conditions and metabolic processes of the whole organism. Polypharmacy and a large number of medications, the lack of uniform standards for the treatment of ischemic stroke - all this complicates the work of the liver and negatively affects the status of patients with cerebral ischemic disasters. The experiment reproduced incomplete cerebral ischemia to create a mechanism of reperfusion injury to the brain. When studying morphological data, clear relationships and similarities of structural disorders in the liver and brain tissue were revealed during experimental ischemic stroke and reperfusion in rats. Taking into account the secondary and indirect nature of liver damage during acute ischemic stroke and reperfusion, a clear interdependent relationship has been identified between the identified disturbance of central regulation and the general systemic inflammatory response, which manifests itself morphologically and, therefore, functionally.

Key words: Artery, blood circulation, cells, phagocytes, neurons, brain, ischemia, stroke, human, ischemic brain damage, morphological changes in the liver, experiment.

First page

800

Last page

804

For citation:Kholboeva G.B. - MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN THE LIVER IN CEREBRAL ISCHEMIC STROKE//New Day in Medicine 5(67)2024 800-804 https://newdayworldmedicine.com/en/article/3758

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