52 -6 (68) 2024 - Ruzikulov A.K., Irsalieva F.Kh. - BRONCHIAL ASTHMA - EARLY DIAGNOSIS, A MODERN LOOK AT THE PROBLEM

BRONCHIAL ASTHMA - EARLY DIAGNOSIS, A MODERN LOOK AT THE PROBLEM

Ruzikulov A.K. - Termez branch of the Tashkent Medical Academy Surkhandarya region

Irsalieva F.Kh. - Tashkent Medical Academy

Resume

Bronchial asthma is one of the pressing problems of modern health care. Today, an estimated 358 million people worldwide suffer from asthma, accounting for 4 to 10 percent of the adult planet's population, and according to some other sources, it was suspected that by 2025 this figure would reach 400 million people. The goal is to develop an early diagnostic method for timely detection of bronchial asthma, prevention of possible complications, early approach to treatment, selection of preventive treatments. The goal is to develop an early diagnostic method for timely detection of bronchial asthma, prevention of possible complications, early approach to treatment, selection of preventive treatments. Research material and methods. The study was carried out in people with bronchial asthma in various regions of Surkhandarya region. According to the study, 64 (100 percent) patients with bronchial asthma participated in the tests, of which 23 (35.9 percent) were male and 41 (64.1 percent) were female. The study carried out methods for collecting objective and subjective materials, in-depth analysis of Anamnesis data, statistical data of disease outbreaks in Surkhandarya region, General blood analysis, serological-Idem examination, method of enhanced radiological examination of the lungs, examination of polymorphism alleles and genotypes of genes IL17A, IL23R, IL17F, spirometry. Results. The most common areas of bronchial asthma are Sarosian, next are the city of Termez, jargon, Sandgrouse, Goldinsoe districts. We were convinced that the main symptoms of bronchial asthma are higher in the level of salinity when compared with the control group, which is observed in almost all patients. It should be noted that during the period of sensitivity, patients experienced a lot of psychopathological conditions, faced with anxiety, fear of death, insecurity, and in the absence of sensitivity, mainly with a state of depression. among those participating in the study, we found that the mother, father or close relatives have these diseases, the most interesting is that in patients with an allergic or hereditary predisposition to one of the parents, the clinical course of the BA is mild or moderate, but in both the father and mother, their presence has led to the development of severe and In the pathology of the lungs and bronchi according to spirometry, especially in severe types of bronchial asthma, the vital capacity of the lungs, the maximum Examiner flow and the maximum volume of forced breathing decrease sharply in full-fledged breathing volume, which negatively affects not only the lungs themselves, but the brain, heart, blood and general body, completely damaging tissue performance.

Keywords: bronchial asthma, eatra diagnosis, spirometry, genetic analysis, serological examination

First page

302

Last page

312

For citation:Ruzikulov A.K., Irsalieva F.Kh. - BRONCHIAL ASTHMA - EARLY DIAGNOSIS, A MODERN LOOK AT THE PROBLEM//New Day in Medicine 6(68)2024 302-312 https://newdayworldmedicine.com/en/article/3758

List of References

  1. Akhmedov A.K. Master of Therapy 1st degree D. Kodirov Study of clinical and functional characteristics and prevalence of chronic non-specific lung diseases in young people //"Экономика и социум" 2022;4(95) www.iupr.ru
  2. Авдеев С.Н. Распространенность, заболеваемость, фенотипы и другие характеристики тяжелой бронхиальной астмы в Российской Федерации. /С.Н. Авдеев [и др.] //Пульмонология. 2018;28(3):341-358.
  3. Avdeev S.N., Nenasheva N.M., Zhudenkov K.V. et al. Prevalence, incidence, phenotypes and other characteristics of severe bronchial asthma in the Russian Federation. //Pulmonology. 2018;28(3):341-358. DOI: 10.18093/0869-0189-2018-28-3-341-358.
  4. Барановская Т.В. Тяжелая бронхиальная астма – 2018. Согласительный доклад объединенной группы экспертов Ассоциации русскоговорящих специалистов в области респираторной медицины, Российского респираторного общества, Российской ассоциации аллергологов и клинических иммунологов / Т.В. Барановская [и др.] //Практ. пульмонология. 2018;3:52-64.
  5. Визель А.А. Бронхиальная астма с поздним началом: возможности персонифицированной терапии / А.А. Визель [и др.] //Практическая пульмонология. 2018;1:12-16.
  6. Ganiev B.S. The development of primary health care in Uzbekistan. International Conference Bridge to science: research works Conference Proceedings April, 15. 2019 San Francisco, USA p.149.
  7. Ganiev B.S. The introduction of modern innovative health standards in the activities of primary health care. For participation in international conference bridge to science: research works April 15, 2019, San Francisco, USA.
  8. Global Initiative for Asthma (GINA). 2018 GINA Global Strategy for Asthma Management and Prevention (GINA). (Electronic resource.)
  9. Global Initiative on Bronchial Asthma (GINA) 2020 Online Appendix. URL: https://ginasthma.org/wp-content/uploads/2020/04/GINA-2020-Appendix_final-wms.pdf (access date: 17.06.2021).
  10. Заболеваемость всего населения России в 2017 году с диагнозом, установленным впервые в жизни. Статистические материалы. М.; 2018. [Morbidity of the entire population of Russia in 2017 with a diagnosis established for the first time in life/ Statistical materials. Moscow; 2018 (in Russ.)].
  11. Лещенко И.В. Бронхиальная астма: простые решения сложных вопросов //Мед. совет. 2019;6:52-57.
  12. Салухов В.В., Харитонов М.А., Зайцев А.А., Рамазанова К.А., Асямов К.В. Современные представления о бронхиальной астме Вестник Российской Военно-Медицинской Академии 2020;2(70):227-234.
  13. Федеральные клинические рекомендации по диагностике и лечению бронхиальной астмы / Под ред. А.Г. Чучалина. – М.: Росс. респираторное общество. 2019;97.
  14. Шустов С.Б. Нарушения функции внешнего дыхания при различных формах легочной патологии / С.Б. Шустов [и др.] //Пульмонология. 2017;27(3):410-418.
  15. Chipps B.E. Benralizumab efficacy by atopy status and serum immunoglobulin E for patients with severe, uncontrolled asthma / В.Е. Chipps [et al.] //Ann. Allergy Asthma Immunol. 2018;120(5):504-511.
  16. Craig S.S., Dalziel S.R., Powell CVE, Graudins A, Babl FE, Lunny C. Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews. //Cochrane Database of Systematic Reviews 2020, Issue 8. Art. No.: CD012977. DOI: 10.1002/14651858.CD012977.pub2.
  17. Enilari O., Sinha S. The Global Impact of Asthma in Adult Populations. //Annals of Global Health. 2019;85(1):1-7. DOI: 10.5334/aogh.2412.
  18. European Respiratory Society. Global Strategy for Asthma Management and Prevention. Revised 2019 //Lancet. 2019;394:919-928.
  19. Israel E.K. Severe and Difficult-to-Treat Asthma in Adults / Е.К. Israel [ et al.] //N. Engl. J. Med. 2017;377(10):965-976.
  20. Mamasoliev N.S., Ganiev B.S., Kalandarov D.M., Olimova N.A. Preventive problems of bronchial asthma Preventive Medicine and HealthIssue –2No 2(2023) /-С.5-10. ISSN 2181-3663

    file

    download