55 -6 (68) 2024 - Kim O.V., Yusupov Sh.A. - FEATURES OF COLLAGEN PROTEIN METABOLISM

FEATURES OF COLLAGEN PROTEIN METABOLISM

Kim O.V. - Samarkand State Medical University

Yusupov Sh.A. - Samarkand State Medical University

Khalikov K.M. - Samarkand State Medical University

Resume

This article discusses the issues of the structural organization of bone tissue, bone morphogenic proteins, the features of the structure and metabolism of collagen proteins, their prevalence in the body, as well as the possibility of using them as markers to assess the intensity of bone tissue formation and resorption.

Keywords: Bone tissue, collagen, bone markers, modeling, remodeling.

First page

324

Last page

329

For citation:Kim O.V., Yusupov Sh.A., Khalikov K.M. - FEATURES OF COLLAGEN PROTEIN METABOLISM//New Day in Medicine 6(68)2024 324-329 https://newdayworldmedicine.com/en/new_day_medicine/6-68-2024

List of References

  1. Ансари Н.А. Неферментативное гликирование белков: от диабета до рака / Н.А. Ансари, З. Рашид //Биомедицинская химия. 2010;56(2):168-178.
  2. Маянский, Д.Н. Лекции по клинической патологии /Руководство для врачей. – М.: ГЭОТАР – Медиа, 2007; 464 с.
  3. Пикалюк В.С. Современные представления о биологии и функции костной ткани / В.С. Пикалюк, С.О. Мостовой //Таврический медико-биологический вестник. 2006;9(3):186-189.
  4. Северин Е.С. Биологическая химия / Е.С. Северин, Т.Л. Алейникова, Е.В. Осипов, С.А. Силаева. / М.: ООО «Медицинское информационное агентство», 2008; 364с.
  5. Торопцова Н.В. Прогноз эффективности терапии с помощью биохимических маркёров костного метаболизма /Н.В. Торопцова, О.А. Никитинская //Украинский ревматологический журнал. 2011;3(45):35-38.
  6. Юсупов Ш.А. Острый гематогенный остеомиелит у детей. //Educational Research in Universal Sciences. 2024;3(2):330-335.
  7. Atkinson M.A. The Pathogenesis and Natural History of Type 1 Diabetes / M.A. Atkinson //Cold Spring Harb Perspect Med. 2012;2:11.
  8. Boudko S.P. Autosomal Recessive Osteogenesis Imperfecta: A Puzzle for Bone Formation, Structure and Function /S.P. Boudko, E.N. Pokidysheva, H.P. Bächinger //Curr Genet Med Rep. 2013;1:239-246.
  9. Butolin E. G. et al. Role of biomarkers of organic matrix of bone tissue in chronic hematogenous osteomyelitis in children. //European journal of molecular medicine. 2022;2(5).
  10. Chung H.J. Collagen Fibril Formation / H.J. Chung, A. Steplewski, K.Y. Chung [et al.] // J. Biol. Chem. 2008;283(38):25879-25886.
  11. Chung H.J. Collagen Fibril Formation / H.J. Chung, A. Steplewski, K.Y. Chung [et al.] // J. Biol. Chem. 2008;283(38):25879-25886.
  12. Crockett J.C. Bone remodelling at a glance / J.C. Crockett, M.J. Rogers, F.P. Coxon [et al.] // J. Cell. Sci. 2011;124(7):991-998.
  13. Howes J. The Recognition of Collagen and Triple-helical Toolkit Peptides by MMP-13 / J. Howes, D. Bihan, D.A. Slatter [et al.] //J. Biol. Chem. 2014;289(35):24091-24101.
  14. Kim O. V., Fayzullayeva X. B. Possibilities of clinical application of organic bone matrix in chronic hematogenous osteomyelitis in children //SCHOLAR. 2023;1(29):164-172.
  15. Nakanishi K. Combination of HLA-A24, -DQA1*03, and -DR9 Contributes to Acute-Onset and Early Complete β-Cell Destruction in Type 1 Diabetes: Longitudinal Study of Residual β-Cell Function / K. Nakanishi, H. Inoko //Diabetes. 2006;55(6):1862-1868.
  16. Panwar P. Effects of Cysteine Proteases on the Structural and Mechanical Properties of Collagen Fibers / P. Panwar, X. Du, V. Sharma [et al.] //J. Biol. Chem. 2013;288(8):5940-5950.
  17. Parisuthiman D. Biglycan Modulates Osteoblast Differentiation and Matrix Mineralization / D. Parisuthiman, Y. Mochida, W. R. Duarte [et al.] //J. Bone Miner. Res. 2005;20(10):1878-1886.
  18. Sarkar S.K. Single-molecule Tracking of Collagenase on Native Type I Collagen Fibrils Reveals Degradation Mechanism / S.K. Sarkar, B. Marmer, G. Goldberg [et al.] //Curr Biol. 2012;22(12):1047-1056.
  19. Schett G. Cells of the synovium in rheumatoid arthritis. Osteoclasts / G. Schett //Arthritis Res. Ther. 2007;9.
  20. Toirovich M. S., Vladislavovna K. O. Significance of bone tissue organic matrix biomarkers in acute hematogenous osteomyelitis in children //Science and Innovation. 2024;3(2):88-92.

    file

    download