60 -6 (68) 2024 - Toshev F.N., Saidov F.A. - PATHOLOGICAL PARAMETERS OF SYNOVIAL FLUID BEFORE AND AFTER TREATMENT IN PATIENTS WITH GONARTHROSIS

PATHOLOGICAL PARAMETERS OF SYNOVIAL FLUID BEFORE AND AFTER TREATMENT IN PATIENTS WITH GONARTHROSIS

Toshev F.N. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Saidov F.A. - Republican Specialized Traumatology and Orthopedics Scientific and Practical Medical Center

Resume

Gonarthrosis of the knee joint is a disease that primarily affects hyaline cartilage. Over time, it begins to collapse, ceasing to perform its main function. As a result, destruction occurs in other components of the joint and its deformation occurs. Gonarthrosis of the knee joint is the most common disease of all types of arthroses. Some people think that the cause of the development of gonarthrosis is the deposition of salts in the joints, but orthopedic traumatologists believe that the deposition of salts itself is a secondary process and becomes the cause of pain during the development of gonarthrosis, being localized in the places of attachment of ligaments and tendons. Gonarthrosis of the knee joint affects mainly women after 40 years of age, but this non-infectious degenerative disease also occurs in men. A special risk group includes people who are overweight or work in conditions of frequent hypothermia. Gonarthrosis can also occur in people who engage in active sports, including as a result of injuries and injuries

Keywords: gonarthrosis, synovial fluid, macrophage, Romanowsky-Giemsa stain, synovial mucin.

First page

352

Last page

357

For citation:Toshev F.N., Saidov F.A. - PATHOLOGICAL PARAMETERS OF SYNOVIAL FLUID BEFORE AND AFTER TREATMENT IN PATIENTS WITH GONARTHROSIS//New Day in Medicine 6(68)2024 352-357 https://newdayworldmedicine.com/en/new_day_medicine/6-68-2024

List of References

  1. Alindon T.E., Snow S., Cooper C., Dieppe P.A. Radio¬graphic patterns of osteoarthritis of the knee joint in the community: the importance of the patellofemoral joint //Ann. Rheum. Dis. 2012;51:844-849.
  2. Engebretsen L., Britt E., Holm I. The prevalence of pa¬tellofemoral osteoarthritis 12 years after anterior cruciate ligament reconstruction //Knee Surg. Sports Traumatol¬ogy Arthroscopy. 2013;21:942-949.
  3. Elahi S., Cahue S., Felson D.T., Engelman L., Sharma L. The association between varus-valgus alignment and patellofemoral osteoarthritis //Arthritis Rheum. 2000;43(8):1874-1880.
  4. Fife R.S., Osteoarthritis - epidemiology, pathology, and pathogenesis // Primer on the Rheumatic Diseases / Ed. by J.H. Klippel, J.H. Stone, L.J. Crofford, P.H. White. //Atlanta: Arthritis Foundation, 2001;216-217.
  5. Hochberg M.C. Osteoarthritis - clinical features and treatment // Primer on the Rheumatic Disea¬ses / Ed. by J.H. Klippel, J.H. Stone, L.J. Crofford, P.H. White. //Atlanta: Arthritis Foundation, 2011;218-221.
  6. Sonne-Holm S., Jacobsen S. Osteoarthritis of the first carpometacarpal joint: a study of radiology and clinical epidemiology. Results from the Copenhagen Osteoarthritis Study //Osteoarthritis Cartilage. 2016;14(5):496-500.
  7. Lawrence J.S., Bremner J.M., Bier F. Osteo-arthro- sis. Prevalence in the population and relationship between symptoms and x-ray changes //Ann. Rheum. Dis. 2009;25(1):1-24.
  8. Wakefield R.J., Green M.J., Marzo-Ortega H. et al. Should oligoarthritis be reclassified. Ultrasound reveals a high prevalence of subclinical disease //Ann. Rheum. Dis. 2004;63(4):382-385.
  9. Persiani S., Cancianji L., Ricci W.L. et al. Glucosamine does not inhibit or induce human cytochromes P450. //Drug. Metab. Rev. 2006;38(2):255.
  10. Rozendaal R.M., Uitterlinden E.J. et al. Glucosamine sul¬phate effects on joint space narrowing, pain and function in patients with hip osteoarthritis; subgroup analyses of a randomized controlled trial. //Osteoarthritis Cartilage. 2009;17:427-432.
  11. Sawitzke A.D., Shi H., Finco M.F. et al. The effect of glu¬cosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chon-droitin arthritis intervention trial. //Arthritis. Rheum. 2018;58:3183-3191.
  12. Zhang W., Nuki G., Moskowitz R.W. et al. OARSI rec¬ommendations for the management of hip and knee oste¬oarthritis: part III: Changes in evidence following system¬atic cumulative update of research published through Jan¬uary 2009. //Osteoarthritis Cartilage. 2010;18:476-499.

    file

    download