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  • 19 -7 (69) 2024 - Babamuradova Z.B., Shodikulova G.Z. - FEATURES OF THE IMMUNE SYSTEM IN PATIENTS WITH RHEUMATOLOGICAL DISEASES AND WAYS FOR THEIR CORRECTION

19 -7 (69) 2024 - Babamuradova Z.B., Shodikulova G.Z. - FEATURES OF THE IMMUNE SYSTEM IN PATIENTS WITH RHEUMATOLOGICAL DISEASES AND WAYS FOR THEIR CORRECTION

FEATURES OF THE IMMUNE SYSTEM IN PATIENTS WITH RHEUMATOLOGICAL DISEASES AND WAYS FOR THEIR CORRECTION

Babamuradova Z.B. - Samarkand State Medical University Uzbekistan

Shodikulova G.Z. - Samarkand State Medical University Uzbekistan

Resume

Today, according to the health organization, rheumatological diseases are one of the leading causes of disability worldwide. The role of polymorphic genes of the autoimmune system (IL17A, IL17F, IL23R) and the cytokine system (TNFα, IL 1β, IL4, IL6, IL10) in the differential clinical course and severity of RD disease and the correlation of polymorphic genes of the cytokines IL1β, IL6, IL17A, TNFα with clinical symptoms have not been studied. Based on the above, it is possible to conduct scientific research aimed at early diagnosis of RA, SLE and AS among RDs, studying the characteristics of clinical, laboratory and immunogenetic manifestations, and increasing the effectiveness of treatment.

Key words: rheumatological diseases, rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis, cytokines, autoimmune inflammation, genetically engineered biological drugs.

First page

114

Last page

120

For citation:Babamuradova Z.B., Shodikulova G.Z. - FEATURES OF THE IMMUNE SYSTEM IN PATIENTS WITH RHEUMATOLOGICAL DISEASES AND WAYS FOR THEIR CORRECTION//New Day in Medicine 7(69)2024 114-120 https://newdayworldmedicine.com/en/new_day_medicine/7-69-2024

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