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  • 49 -1 (63) 2024 - J.M. Prieto Gonzalez, G.K. Sodikova, J.E. Mirdjuraev - EFFICIENCY OF THALAMIC THERMAL ABLATION WITH MRI-GUIDED FOCUSED ULTRASOUND IN PATIENTS WITH ESSENTIAL TREMOR

49 -1 (63) 2024 - J.M. Prieto Gonzalez, G.K. Sodikova, J.E. Mirdjuraev - EFFICIENCY OF THALAMIC THERMAL ABLATION WITH MRI-GUIDED FOCUSED ULTRASOUND IN PATIENTS WITH ESSENTIAL TREMOR

EFFICIENCY OF THALAMIC THERMAL ABLATION WITH MRI-GUIDED FOCUSED ULTRASOUND IN PATIENTS WITH ESSENTIAL TREMOR

J.M. Prieto Gonzalez - University of Santiago de Compostella (Spain) Colexio de San Xerome

G.K. Sodikova - Tashkent Pediatric Medical Institute

J.E. Mirdjuraev - Tashkent Pediatric Medical Institute

Resume

Background. We observed 40 patients with essential tremor who received unilateral thalamic thermal ablation using focused ultrasound under visual control of magnetic resonance imaging. Methods. The patients were examined and diagnosed with "essential tremor" with the identification of the questionnaire total score severity of essential tremor. Results. When comparing the results obtained in patients before and after treatment, a significant improvement in the total ET score was obtained in both women and men. However, it should be noted that ET parameters associated with the left hand (left hand tremor, left hand drawing, left hand drinking) remained unchanged, which is most likely associated with unilateral thalamic thermal ablation. Conclusions. Treatment of essential tremor with MRI-guided focused ultrasound is an effective and safe treatment option. However, it does not affect the tremor on the opposite side of the thalamic thermal ablation and has reversible complications in a small proportion of patients during the thalamic thermal ablation procedure and some persistent side effects from the treatment.

Keywords: essential tremor, unilateral thalamic thermal ablation, focused ultrasound, magnetic resonance imaging

First page

263

Last page

267

For citation:J.M. Prieto Gonzalez, G.K. Sodikova, J.E. Mirdjuraev - EFFICIENCY OF THALAMIC THERMAL ABLATION WITH MRI-GUIDED FOCUSED ULTRASOUND IN PATIENTS WITH ESSENTIAL TREMOR//New Day in Medicine 1(63)2024 263-267 https://newdayworldmedicine.com/en/new_day_medicine/1-63-2024

List of References

  1. Becktepe J, Gövert F, Balint B, Schlenstedt C, Bhatia K, Elble R, Deuschl G (2021) Exploring interrater disagreement on essential tremor using a standardized tremor elements assessment. // MovDisordClinPract 2021; 8(3):371-376.
  2. Crawford S, Lally C, Petrillo J, Paskavitz J, Louis E. (2020) How many adults in the US have essential tremor? Using data from epidemiological studies to derive age-specific estimates of prevalence [poster 192]. // MovDisordClinPract. 2020; 7(S1):S109.
  3. Erro R, Reich SG (2022) Rare tremors and tremors occurring in other neurological disorders. // J NeurolSci 2022; 19(435):120-200. https://doi.org/10.1016/j.jns.2022.120200
  4. Erro R., Sorrentino C., Russo M. et al. (2022) Essential tremor plus rest tremor: current concepts and controversies. // J Neural Transm 129, 835-846 https://doi.org/10.1007/s00702-022-02516-2
  5. Gallay M.N., Moser D., Jeanmonod D. (2020) MR-guided focused ultrasound cerebellothalamictractotomy for chronic therapy-resistant essential tremor: anatomical target reappraisal and clinical results // Journal of Neurosurgery. 2020; Т.1:1-10.
  6. Gerbasi ME, Eldar-Lissai A, Lyons KE. (2022) Epidemiology of pediatric essential tremor in the United States: a systematic literature review from 2010 to 2020. // Tremor and Other Hyperkinetic Movements. 2022; 12(1):11. DOI: http://doi.org/10.5334/tohm.681
  7. Li JY, Suo XL, Li NN, Lei D, Lu ZJ, Wang L, Peng JX, Duan LR, Jing-Xi Y-J, Gong QY, Peng R (2021) Altered spontaneous brain activity in essential tremor with and without resting tremor: a resting-state fMRI study. MAGMA 2021; 34(2):201-212. https://doi.org/10.1007/s10334-020-00865-1
  8. Louis ED, McCreary M. (2021) How common is essential tremor? Update on the worldwide prevalence of essential tremor. // Tremor Other Hyperkinet Mov. 2021; 11(1):1-14. DOI: https://doi.org/10.5334/tohm.632
  9. Nisticò R, Quattrone A, Crasà M, De Maria M, Vescio B, Quattrone A (2022) Evaluation of rest tremor in different positions in Parkinsons disease and essential tremor plus. Neurol Sci. https://doi.org/10.1007/s10072-022-05885-4
  10. Shanker V. (2019) Essential tremor: diagnosis and management. // BMJ. 2019; 366:l4485. DOI: https://doi.org/10.1136/bmj.l4485
  11. Xiong Y, Lin J, Bian X, Lu H, Zhou J, Zhang D, Pan L, Lou X. (2022) Treatment-Specific Network Modulation of MRI-Guided Focused Ultrasound Thalamotomy in Essential Tremor: Modulation of ET-Related Network by MRgFUS Thalamotomy. // Neurotherapeutics. 2022 Oct; 19(6):1920-1931. doi: 10.1007/s13311-022-01294-9. Epub 2022 Sep 9. PMID: 36085538; PMCID: PMC9462640.
  12. FDA official government website: FDA approves first MRI-guided focused ultrasound device to treat essential tremor

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