15 -8 (70) 2024 - Radjabova Z.S. - PATHOPHYSIOLOGY OF CEREBRAL EDEMA

PATHOPHYSIOLOGY OF CEREBRAL EDEMA

Radjabova Z.S. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The literature review focuses on the current understanding of the pathogenetic role of the glymphatic system (GS) in the development of cerebral edema in TBI and ischemic and hemorrhagic strokes. We discussed recent research suggesting that glymphatic function is suppressed in brain pathologies and that deficient glymphatic function, in turn, may contribute to the development of cerebral edema in TBI and stroke. New understanding of the pathophysiology of how trauma and stroke affect GS function and how this function is decompensated in brain pathologies should lead to the development of new preventive and new therapeutic targets.

Key words:cerebral edema, glymphatic system, astrocytes, stroke, traumatic brain injury.

First page

77

Last page

83

For citation:Radjabova Z.S. - PATHOPHYSIOLOGY OF CEREBRAL EDEMA//New Day in Medicine 8(70)2024 77-83 https://newdayworldmedicine.com/en/new_day_medicine/8-70-2024

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