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  • 51 -8 (70) 2024 - Mustafakulov I.B., Khaitov A.A. - MORPHOLOGICAL ASSESSMENT OF TISSUE CHANGES IN RECURRENT HERNIA AFTER ALLOPLASTY

51 -8 (70) 2024 - Mustafakulov I.B., Khaitov A.A. - MORPHOLOGICAL ASSESSMENT OF TISSUE CHANGES IN RECURRENT HERNIA AFTER ALLOPLASTY

MORPHOLOGICAL ASSESSMENT OF TISSUE CHANGES IN RECURRENT HERNIA AFTER ALLOPLASTY

Mustafakulov I.B. - Samarkand State Medical University

Khaitov A.A. - Termez branch of the Tashkent Medical Academy Surkhandarya

Resume

A morphological analysis of biopsies taken from the area of surgical intervention was carried out in 64 patients who underwent repeat hernia alloplasty. The study included early (up to 6 months) and late (more than 6 months) relapses. It turned out that tissue reactions at the interface between the fiber and the endoprosthesis play a key role in the development of both early and late relapses. Particularly significant is the macrophage reaction, which maintains a state of chronic aseptic inflammation and processes of “false biodegradation” directed both at the implant itself and at the surrounding connective tissue. This contributes to the formation of gaps and rupture loci in fibrous-modified connective tissue, which, along with factors affecting the position of the endoprosthesis (in lay, on lay), contributes to the occurrence of relapses.

Key words: postoperative ventral hernia, relapse, morphological study

First page

278

Last page

283

For citation:Mustafakulov I.B., Khaitov A.A. - MORPHOLOGICAL ASSESSMENT OF TISSUE CHANGES IN RECURRENT HERNIA AFTER ALLOPLASTY//New Day in Medicine 8(70)2024 278-283 https://newdayworldmedicine.com/en/new_day_medicine/8-70-2024

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