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  • 69 -8 (70) 2024 - Rajabova D.Dzh. - A NEW METHOD OF IMMUNO-BIOCHEMICAL DIAGNOSIS OF CHOLESTATIC SYNDROME IN OUTPATIENT PRACTICE

69 -8 (70) 2024 - Rajabova D.Dzh. - A NEW METHOD OF IMMUNO-BIOCHEMICAL DIAGNOSIS OF CHOLESTATIC SYNDROME IN OUTPATIENT PRACTICE

A NEW METHOD OF IMMUNO-BIOCHEMICAL DIAGNOSIS OF CHOLESTATIC SYNDROME IN OUTPATIENT PRACTICE

Rajabova D.Dzh. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Cholestatic syndrome is a complex condition characterized by a violation of the normal outflow of bile, which leads to the accumulation of bile acids in the blood and tissues of the body. This disease can be caused by various factors, including pathologies of the liver, biliary tract and other organs. In outpatient practice, the diagnosis of cholestatic syndrome is a significant difficulty, since traditional methods such as biochemical tests and ultrasound often do not provide sufficiently high accuracy and efficiency. This study presents a new method of immuno-biochemical diagnosis of cholestatic syndrome, adapted for use in outpatient settings. The main goal of the development was to create an affordable, simple and highly effective diagnostic method that would allow timely detection of cholestatic syndrome and effective monitoring of patients' condition. The new method is based on the use of specific biomarkers that reflect the functional state of the liver and biliary tract. The method involves analyzing the levels of certain molecules in the blood serum, such as bile acids, alkaline phosphatase and gamma-glutamyltransferase, as well as specific antibodies associated with the cholestatic process. These markers have high sensitivity and specificity, which makes it possible to detect cholestatic syndrome in the early stages of the disease. The study demonstrated that the new method can significantly improve the accuracy of diagnosis compared to traditional tests, as well as reduce the time to obtain results. The study involved 150 patients with suspected cholestatic syndrome who applied to outpatient medical institutions. The patients were divided into groups depending on the clinical diagnosis and stage of the disease. The new diagnostics were applied along with traditional methods to compare its effectiveness and accuracy. The sensitivity and specificity of the new method were evaluated, as well as its execution time and cost compared to conventional diagnostic procedures. The results showed that the new method of immuno-biochemical diagnostics has a high sensitivity (90%) and specificity (85%), which makes it possible to more accurately identify the cholestatic syndrome and determine its stage. The method also demonstrated a reduction in the time to receive results to several hours, which significantly speeds up the diagnostic process and allows faster treatment decisions. Compared to traditional methods, the new test also proved to be more cost-effective.

Keywords: cholestatic syndrome, immuno-biochemical diagnostics, outpatient practice, markers, diagnostics.

First page

385

Last page

391

For citation:Rajabova D.Dzh. - A NEW METHOD OF IMMUNO-BIOCHEMICAL DIAGNOSIS OF CHOLESTATIC SYNDROME IN OUTPATIENT PRACTICE//New Day in Medicine 8(70)2024 385-391 https://newdayworldmedicine.com/en/new_day_medicine/8-70-2024

List of References

  1. Rakhmatova D. B., Rakhmatova D. B. "Main" Symptoms and leading clinical options for the flow of acute coronary syndromes in women //Asian Journal of Multidimensional Research (AJMR). 2019;8(11):69-74.
  2. Rakhmatova D. B. Analysis of the risk factors of Chd in persons over 60 years among the population of the city of Bukhara //Asian studies. Индия. 2019;1:33-38.
  3. Rakhmatova D. B., Zikrillaev F. A. Determine the value of risk factors for myocardial infarction //Fan, Ta'lim, Madaniyat va Innovatsiya. 2022;1(4):23-28.
  4. Рахматова Д.Б., Аслонова М.Р. Современные методы медицинской реабилитации пациентов с артериальной гипертензией //Биология и интегративная медицина. 2018;3:110-117.
  5. Рахматова Д. Б. и др. Оценка факторов риска ибс у лиц старше 60 лет среди населения города Бухары //Теория и практика современной науки. 2018;5(35):704-708.
  6. Рахматова Д. Б., Раджабова Г. Х. Анализ факторов риска ИБС у лиц старше 60 лет среди населения города Бухары //Биология и интегративная медицина. 2019;3(31):37-42.
  7. Рахматова Д. Б. Гранат как лечебное средство в народной и древней медицине //Биология и интегративная медицина. 2022;1(54):157-168.
  8. Rakhmatova D. B., Rakhmatova D. B. "Main" Symptoms and leading clinical options for the flow of acute coronary syndromes in women //Asian Journal of Multidimensional Research (AJMR). 2019;8(11):69-74.
  9. Rakhmatova D. B. Scientific and practical significance of acute myocardial infarction among the population of elderly and old age //Globalization, the State and the Individual. 2022;29(1):84-89.

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