74 -8 (70) 2024 - Ikhtiyarova G.A., Rozikova D.K. - ANALYSIS OF GUT MICROBIOTA IN PREGNANT WOMEN WITH EMBRYO-CHORIAL INSUFFICIENCY

ANALYSIS OF GUT MICROBIOTA IN PREGNANT WOMEN WITH EMBRYO-CHORIAL INSUFFICIENCY

Ikhtiyarova G.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Rozikova D.K. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The aim of the study. To compare the state of intestinal microbiocinosis in pregnant women with embryochorionic insufficiency and in pregnant women with a physiological pregnancy Materials and methods. Currently, gut dysbiosis is extensively discussed in the literature; however, several contentious issues regarding its clinical significance remain unresolved. Recent publications have explored the potential role of systemic endotoxemia, which arises from gut dysbiosis, in the pathogenesis of pregnancy loss. The study was conducted at the Gynecology Department of the Bukhara City Maternity Complex during the period from 2023 to 2024. It involved the examination of medical records of patients admitted for inpatient treatment due embriochorial insuddiciency Conclusion. Thus, microbiological disorders in the intestinal biocenosis in patients with threatened miscarriage were associated with a significant decrease in the amount of normal flora against the background of an increased content of opportunistic microorganisms with a high pathogenic potential and their associations. The intestinal microflora during physiological pregnancy was characterized mainly by a decrease in the intensity of colonization of the large intestine by lacto- and bifidobacteria.

Keywords: embryo-chorial insufficiency, missed miscarriage, threatened spontaneous abortion, endotoxemia, gut dysbiosis

First page

416

Last page

419

For citation:Ikhtiyarova G.A., Rozikova D.K. - ANALYSIS OF GUT MICROBIOTA IN PREGNANT WOMEN WITH EMBRYO-CHORIAL INSUFFICIENCY//New Day in Medicine 8(70)2024 416-419 https://newdayworldmedicine.com/en/new_day_medicine/8-70-2024

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