38 -9 (71) 2024 - I.H. Mamatkulov, Z.I. Berdyaeva, G.H.Rajabov - EFFECTIVE APPROACHES TO ELIMINATING HIV INFECTION

EFFECTIVE APPROACHES TO ELIMINATING HIV INFECTION

I.H. Mamatkulov - Tashkent Research Institute of Vaccines and Serums Uzbekistan

Z.I. Berdyaeva - Tashkent Research Institute of Vaccines and Serums Uzbekistan

G.H.Rajabov - Tashkent Research Institute of Vaccines and Serums Uzbekistan

Resume

The article highlights the results of a new unconventional approach to studying the causes of the development of immunodeficiency in patients with HIV infection and its elimination. In particular, data have been obtained confirming that the worsening of immunodeficiency in HIV infection is associated with chronic anergy of lymphocytes. In particular, data have been obtained confirming that the worsening of immunodeficiency in HIV infection is associated with chronic anergy of lymphocytes. The use of a locally produced biologically active food supplement relieved chronic anergy of lymphocytes, provided a significant and reliable reduction in the viral load in patients, and ensured a reliable restoration of the immune activity of T cells.

Keywords: HIV infection, immunodeficiency, anergy, T-lymphocytes, phagocytosis, viral load.

First page

191

Last page

195

For citation:I.H. Mamatkulov, Z.I. Berdyaeva, G.H. Rajabov - EFFECTIVE APPROACHES TO ELIMINATING HIV INFECTION//New Day in Medicine 9(71)2024 191-195 https://newdayworldmedicine.com/en/new_day_medicine/9-71-2024

List of References

  1. Алиев Б.Р., Мусабаев Э.И., Рахманов М.И., Байжанов А.К., Холдаров З.А. Особенности изменения содержания СД4 лимфоцитов у больных ВИЧ/СПИД с грибковыми заболеваниями //Инфекция, иммунитет и фармакология. - Ташкент, 2010;1-2:27-30.
  2. Атабеков Н.С., Маткаримов Б.Д., Ражабов Г.Х., Курбанов Б.Ж. «Некоторые особенности распространения ВИЧ-инфекции в Узбекистане //Материалы республиканской Научно-практической конференции «Профилактик тиббиёт: кеча, бугун ва эртага». – Андижан, 2015; С. 54.
  3. Байжанов А.К. Резистентность вируса иммунодефицита человека к антиретровирусной терапии у больных ВИЧ-инфекцией //Журнал теоретической и клинической медицины. – Ташкент, 2014;1(3):275-277.
  4. Беляков Н. А., Волкова Г. В., Дворак С. И., Жолобов В. Е. Эпидемия ВИЧ-инфекции // Вирус иммунодефицита человека – медицина - СПб, 2010; 573-592.
  5. Вартбург М. К. Коварный вирус //Мединский журнал: Знание-сила. - Москва, 2010;11:65.
  6. Залялиева М. В. Иммунологический мониторинг и генотипические особенности ВИЧ-инфекции в Узбекистане: Автореф. дис. ...д-ра биол. наук. - Ташкент, 2008; 40 с.
  7. Appay V., Sauce D. Immune activation and inflammation in HIV-1 infection: causes and consequences // II The Journal of Pathology. 2008;214(2):231-241.
  8. Arts E.J., Hazuda D.J.. HIV-1 Antiretroviral Drug Therapy //Cold.Spr.Harb.Persp. Med, 2012;(4):7161.
  9. Bannister W.P., Cozzi-Lepri A., Clotet В., Mocroft A. Transmitted drug resistant HIV-1 and association with virologic and CD4 cell count response to combination antiretroviral therapy in the EuroSIDA Study //J. Acquir. Immune Defic. Syndr. 2008;48(3):324-33.
  10. Bennett D.E., Bertagnolio S., Sutherland D., Gilks C.F. The World Health Organizations global strategy for prevention and assessment of HIV drug resistance //Antiviral Therapy. 2008;13(2):1-13.
  11. British HIV Association Guidelines //HIV Medicine. 2008;9:563-608.

    file

    download