59 -9 (71) 2024 - Urokov Sh.T., Dzhuraev I.B. - MORPHOLOGICAL FEATURES OF THE GASTRIC MUCOSA IN PATIENTS IN SEVERE CONDITION ON ARTIFICIAL VENTILATION
MORPHOLOGICAL FEATURES OF THE GASTRIC MUCOSA IN PATIENTS IN SEVERE CONDITION ON ARTIFICIAL VENTILATION
Urokov Sh.T. - Bukhara State Medical Institute named after Abu Ali ibn Sina
Dzhuraev I.B. - Republican Scientific Center for Emergency Medical Care of the Navoi Branch Uzbekistan
Babanazarov U.T. - Bukhara State Medical Institute named after Abu Ali ibn Sina
Resume
It is well known in medical practice that the gastrointestinal tract (GIT) performs not only a digestive function. The GIT is an important endocrine organ that synthesizes many hormones involved in the regulation of protein, fat and carbohydrate metabolism, exerting a systemic effect on the body. The wall of the GIT contains about 100 million neurons that constantly control its functions, as well as about 60-70% of the body's lymphoid tissue, which ensures an important role of the GIT in immune defense. There is a convincing connection between the state of the gastrointestinal tract and the development of a systemic inflammatory response, as well as multiple organ failure caused by microcirculation disorders in the villous layer of the intestine and high tissue sensitivity to hypoxia (Swank G.M., Deitch E.A., 1996). In this review article, we will consider the relevance of studying the gastric mucosa in patients in severe situations on artificial ventilation.
Key words: hypoxia, lymphoid tissue, inflammatory process, erosions, ulcers.
First page
330
Last page
336
For citation:Urokov Sh.T., Dzhuraev I.B., Babanazarov U.T. - MORPHOLOGICAL FEATURES OF THE GASTRIC MUCOSA IN PATIENTS IN SEVERE CONDITION ON ARTIFICIAL VENTILATION//New Day in Medicine 9(71)2024 330-336 https://newdayworldmedicine.com/en/new_day_medicine/9-71-2024
List of References
- Sedykh A. A. "Features of the structure of the stomach." Theses, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/55346.
- Гула Виктория Ивановна. "Літературні відомості про морфологію шлюнка." Тезисы, Сумський державний університет, 2015. http://essuir.sumdu.edu.ua/handle/123456789/42116.
- Uspenskiĭ VM, Shcherbak SG, Mironov IuA, Golofeevskĭ VIu, Sergeev ST, Antropov VI. Funktsiona'no-morfologicheskaia kharakteristika pishchevaritel'noĭ reaktsii slizistoĭ obolochki zheludka [Functional and morphological characteristics of the digestive reaction of gastric mucosa]. //Arkh Anat Gistol Embriol. Jul 1990;99(7):21-31. Russian. PMID: 2252432.
- Cheli, R., Perasso, A., Giacosa, A. (1987). Normal Stomach: Morphology. In: Gastritis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71845-8_2
- Sakaki S, Lida Y, Okasaki J, Kanamura S, Takemoto T (1978) Magnifying endoscopic observation of the gastric mucosa, particularly in patients with atrophic gastritis. //Endoscopy 1978;10:169-275.
- Mainguet P, Moulinier B (1982) Méthodologie endoscopique dans l’exploration des gastrites. //Acta Endoscopica 1982;12:97-100.
- Takemoto T, Sakaki N (1982) High magnification. In: Kawai K (ed) Frontiers in gastrointestinal endoscopy. Olympus, Tokyo.
- Vassallo, G., Capella, C. Solcia, E. Endocrine cells of the human gastric mucosa. Z. Zellforsch. 118, 49–67 (1971). https://doi.org/10.1007/BF00331766
- Anatomy and physiology of the stomach. Soybel DI. Surg Clin North Am. 2005 Oct;85(5):875-94, v. doi: 10.1016/j.suc.2005.05.009. PMID: 16139026
- Hunt RH, Camilleri M, Crowe SE, El-Omar EM, Fox JG, Kuipers EJ, Malfertheiner P, McColl KE, Pritchard DM, Rugge M, Sonnenberg A, Sugano K, Tack J. The stomach in health and disease. Gut. 2015 Oct;64(10):1650-68. doi: 10.1136/gutjnl-2014-307595. Epub 2015 Sep 4. PMID: 26342014; PMCID: PMC4835810.
- Ian R. Daniels and William H. Allum The Anatomy and Physiology of the Stomach p-30-34.
- Egle Pirie Reviewer: Nicola McLaren MSc https://www.kenhub.com/en/library/anatomy/stomach-histology
- Leaphart C.L., Tepas J.J. The gut is a motor of organ system dysfunction. //Surgery. 2007;141:563-569.
- Norman K., Pirlich M., Schulzke J.D. et al. Increased intestinal permeability in malnourished patients with liver cirrhosis. //Eur. J. Clin. Nutr. 2012;66:1116-1119.
- Overhaus M., Togel S., Pezzone M.A. et al. Mechanisms of polymicrobial sepsis-induced ileus. //Am. J. Physiol. Gastrointest. Liver Physiol. 2004;287:G685.
- Chapman M.J., Nguyen N.Q., Deane A.M. Gastrointestinal dysmotility: Evidence and clinical management. //Curr. Opin. Clin. Nutr. Metab. Care. 2013;16:209-216.
- Chapman M.J., Fraser R.J., Matthews G. et al. Glucose absorption and gastric emptying in critical illness. //Crit. Care. 2009;13:R140.
- Bouin M., Savoye G., Herve S. et al. Does the supplementation of the formula with fi bre increase the risk of gastro-oesophageal refl ux during enteral nutrition? A human study. //Clin. Nutr. 2001;20(4):307-132.
- Bowling T.E., Cliff B., Wright J.W. et al. The effects of bolus and continuous nasogastric feeding on gastro-oesophageal refl ux and gastric emptying in healthy volunteers: a randomised threeway crossover pilot study. //Clin. Nutr. 2008;27(4):608-613.
- MacLeod J.B., Lefton J., Houghton D. et al. Prospective randomized control trial of intermittent versus continuous gastric feeds for critically ill trauma patients. //J. Trauma. 2007;63(1):57-61.
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