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  • 25 -10 (72) 2024 - Bustanov Sh.Y., Mamataliyev A.R. - PATHO-MORPHOGENESIS OF CARDIOVASCULAR SYSTEM DAMAGE DURING POST-COVID SYNDROME

25 -10 (72) 2024 - Bustanov Sh.Y., Mamataliyev A.R. - PATHO-MORPHOGENESIS OF CARDIOVASCULAR SYSTEM DAMAGE DURING POST-COVID SYNDROME

PATHO-MORPHOGENESIS OF CARDIOVASCULAR SYSTEM DAMAGE DURING POST-COVID SYNDROME

Bustanov Sh.Y. - Andijan State Medical Institute

Mamataliyev A.R. - Andijan State Medical Institute

Resume

In the study, morphological and morfоhometric changes occurring in the myocardium and coronary vessels were studied in the autopsy data of patients who died of post-covid syndrome in different age groups. Decompensation of atherosclerotic changes in the coronary vessels, inflammation of the endothelium, exacerbation of focal inflammations in the myocardium, development of thrombosis and ischemic infarctions were observed in patients with RKS in parallel with increasing age. Atherosclerotic damage, thickness, stenosis, and destructive changes of the coronary artery wall increased with age and showed a strong progression.

Key words: COVID-19, SARS-CoV-2 virus, post - COVID syndrome, cardiovascular system, IUD, acute myocarditis, myocardial infarction, coronary atherosclerosis.

First page

164

Last page

169

For citation:Bustanov Sh.Y., Mamataliyev A.R. - PATHO-MORPHOGENESIS OF CARDIOVASCULAR SYSTEM DAMAGE DURING POST-COVID SYNDROME//New Day in Medicine 10(72)2024 164-169 https://newdayworldmedicine.com/en/new_day_medicine/10-72-2024

List of References

  1. Арутюнов Г.П. Терапевтические аспекты диагностики и лечения заболеваний сердца и сосудов. /М.: ГЭОТАР-Медиа, 2015; 424с.
  2. Бойцов С.А. и др. Клиническая картина и факторы, ассоциированные с неблагоприятными исходами у госпитализированных пациентов с новой коронавирусной инфекцией COVID-19. //Кардиология. 2021;61(2):4-14. https://doi.org/ 10.18087/ cardio.2021.2.n1532.
  3. Козлов И.А. и др. Сердечно-сосудистые осложнения COVID-19. //Вестник анестезиологии и реаниматологии, 2020;17(4):14-22. http://doi.org/10.21292/2078-5658-2020-17-4-14-22.
  4. Костенко Н.А., Камкин Е.Г., Авдеев С.Н. и др. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19 ). /М., 2020; С. 68.
  5. Akhmerov A., Marban E.: COVID-19 and the heart // Circulation Research. 2020;126:1443-1455.
  6. Huang C. et al. Comprehensive health assessment three months after recovery from acute COVID-19. Clin Infect Dis. 2020 Nov 21:ciaa1750. PMID: 33220049 https://doi.org/10.1093/cid/ciaa1750.
  7. Moreno-Pérez O. et al. Post-acute COVID-19 syndrome. Incidence and risk factors: A Mediterranean cohort study. //J Infect. 2021;82(3):378–383. PMID: 33450302 https://doi.org/10.1016/j.jinf.2021.01.004Russian Sklifosovsky Journal of Emergency Medical Care. 2021;10(2):248–258. https://doi.org/10.23934/2223-9022-2021-10-2-248-258
  8. Ruan Q., Yang K., Wang W. et al. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China //Intensive Care Med. 2020; P. 846–848.
  9. Wu Z., Mc Googan J.M. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. //JAMA. 2020 Feb 24. doi: 10.1001/jama.2020.2648.
  10. Xiong T.Y., Redwood S., Prendergast B., Chen M. Coronaviruses and the cardiovascular system: acute and long -term implications //European Heart Journal. 2020;41(19):1798-1800.
  11. Zagidullin N.S., Motloch L.J., Musin T.I., et al.J-waves in acute COVID-19: a novel disease characteristic and predictor of mortality. //PLoS ONE. 2021;16:e0257982. https://doi.org/10.1371/journal.pone.0257982. PMID: 34648510.
  12. Zhao Y.M. et al. Followup study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery. //EClinicalMedicine. 2020;25:100463. PMID: 32838236 https://doi.org/ 10.1016/j.eclinm.2020.100463.

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