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  • 95 -10 (72) 2024 - Niyozova T.A., Kholmurodov D.M. - THE ROLE OF WHOLE GENOME SEQUENCING IN TRACKING E. COLI TRANSMISSION IN PUBLIC HEALTH MICROBIOLOGY

95 -10 (72) 2024 - Niyozova T.A., Kholmurodov D.M. - THE ROLE OF WHOLE GENOME SEQUENCING IN TRACKING E. COLI TRANSMISSION IN PUBLIC HEALTH MICROBIOLOGY

THE ROLE OF WHOLE GENOME SEQUENCING IN TRACKING E. COLI TRANSMISSION IN PUBLIC HEALTH MICROBIOLOGY

Niyozova T.A. - Tashkent Medical Academy

Kholmurodov D.M. - Queen Mary University of London, The William Harvey Research Institute-Faculty of Medicine and Dentistry, Charterhouse square, London

Resume

Purpose: This appraisal focuses on how whole genome sequencing (WGS) influences tracking Escherichia coli (E. coli). It emphasizes its use in pathogen identification outbreak observance and prospective applications in the realm of public health microbiology. Methodology: The research entailed a critical reading of relevant literature. Furthermore, case studies associated with WGS and E. coli transmission were examined. Findings: Whole genome sequencing has notably augmented the detection and subsequent tracking of different E. coli strains. It facilitates the precise determination of strain types. Additionally, WGS aids in identifying resistance genes and virulence factors. Previous case studies underscored its utility in identifying and overseeing outbreaks. Such as the case of the outbreak in 2011. Prospective applications of WGS in public health hold promise, despite existing hurdles. Conclusion: Whole genome sequencing assumes an indispensable role in public health microbiology. It offers insightful data on E. coli transmission. Continued advancements in this field are anticipated. They are likely to bring about further evolutionary changes in outbreak detection surveillance and administration strategies.

Keywords: Genome Sequencing, Escherichia coli Public Health Microbiology, Outbreak Detection Pathogen Surveillance.

First page

533

Last page

538

For citation:Niyozova T.A., Kholmurodov D.M. - THE ROLE OF WHOLE GENOME SEQUENCING IN TRACKING E. COLI TRANSMISSION IN PUBLIC HEALTH MICROBIOLOGY//New Day in Medicine 10(72)2024 533-538 https://newdayworldmedicine.com/en/new_day_medicine/10-72-2024

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