56 -11 (73) 2024 - Salomov N.I., Urokov. Sh.T., Abidov U.O. - TREATMENT OUTCOMES FOR GASTRODUODENAL ULCER BLEEDING IN PATIENTS WITH LIVER CIRRHOSIS

TREATMENT OUTCOMES FOR GASTRODUODENAL ULCER BLEEDING IN PATIENTS WITH LIVER CIRRHOSIS

Salomov N.I. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Bukhara branch of the Republican Scientific Center for Emergency Medical Care Uzbekistan

Urokov. Sh.T. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Bukhara branch of the Republican Scientific Center for Emergency Medical Care Uzbekistan

Abidov U.O. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Bukhara branch of the Republican Scientific Center for Emergency Medical Care Uzbekistan

Resume

Gastric and duodenal ulcer bleeding in patients with liver cirrhosis represents a complex clinical issue due to coagulopathy, portal hypertension, and impaired liver function. The use of combined endoscopic hemostasis methods, including adrenaline injection and vessel clipping, along with prophylactic antibiotic therapy, has proven effective in reducing recurrence rates and mortality. In the main group, the recurrence of bleeding was 5%, and mortality was also 5%, significantly lower compared to the control group (recurrences – 21%, mortality – 18.4%). The primary risk factors for complications and death were the severity of cirrhosis (as classified by the Child-Pugh score) and infectious complications such as spontaneous bacterial peritonitis and pneumonia. Bleeding from gastric and duodenal ulcers in patients with liver cirrhosis and portal hypertension requires a comprehensive approach, including prophylactic endoscopic ligation of varicose veins.

Keywords: Gastric and duodenal ulcers, liver cirrhosis, coagulopathy, recurrence, combined endoscopic hemostasis, adrenaline injection, vessel clipping, antibiotic therapy.

First page

314

Last page

320

For citation:Salomov N.I., Urokov. Sh.T., Abidov U.O. - TREATMENT OUTCOMES FOR GASTRODUODENAL ULCER BLEEDING IN PATIENTS WITH LIVER CIRRHOSIS//New Day in Medicine 11(73)2024 314-320 https://https://newdayworldmedicine.com/en/new_day_medicine/11-73-2024

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