93 -11 (73) 2024 - Akhmedova Sh.M., Badridinova B.K. - EVALUATION OF MORPHOLOGICAL CHANGES IN VIMOS USING IMMUNOHISTOCHEMICAL MARKERS (MACROPHAGE CELL – CD-68) AFTER THE STUDY

EVALUATION OF MORPHOLOGICAL CHANGES IN VIMOS USING IMMUNOHISTOCHEMICAL MARKERS (MACROPHAGE CELL – CD-68) AFTER THE STUDY

Akhmedova Sh.M. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Badridinova B.K. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Objective: Immunohistochemical analysis of morphological changes in the thymus tissue of the control group of 3-month-old purebred rats and the changes in the thymus after 1 day, 1 week and 21 days after brain injury. Methods: 40 prepared histological preparations were selected for immunohistochemical study of thymus tissue samples isolated from purebred rats. Results: In the study, the expression of the immunohistochemical marker CD 68 in thymus tissue 21 days after brain injury of 3-month-old white rats gave the highest rate, which was 28.82% (moderate expression). Conclusions. 20 3-month-old non-white rats selected for the study were selected, and in order to determine the immunohistochemical changes in the thymus tissue after 1 day, 1 week and 21 days after brain injury, micropreparations extracted from 20 non-white rats were immunohistochemically analyzed with the CD 68 marker. the results were studied. In the obtained results, it was found that the immunohistochemical CD 68 marker of macrophages was expressed in thymus cells.

Keywords: thymus, immunity, immunohistochemical CD 68 marker

First page

539

Last page

544

For citation:Akhmedova Sh.M., Badridinova B.K. - EVALUATION OF MORPHOLOGICAL CHANGES IN VIMOS USING IMMUNOHISTOCHEMICAL MARKERS (MACROPHAGE CELL – CD-68) AFTER THE STUDY//New Day in Medicine 11(73)2024 539-544 https://https://newdayworldmedicine.com/en/new_day_medicine/11-73-2024

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