68 -12 (74) 2024 - Zakhidova M.Z. - ONCE AGAIN ABOUT HELICOBACTERIA: RECOMMENDATIONS OF THE MAASTRICHT VI/FLORENCE CONSENSUS ON THE TREATMENT OF HELICOBACTER PYLORI INFECTION
ONCE AGAIN ABOUT HELICOBACTERIA: RECOMMENDATIONS OF THE MAASTRICHT VI/FLORENCE CONSENSUS ON THE TREATMENT OF HELICOBACTER PYLORI INFECTION
Zakhidova M.Z. - Center for the Development of Professional Qualifications of Medical Workers under the Ministry of Health of the Republic of Uzbekistan
Resume
The new Maastricht VI/Florence Consensus clarifies a number of provisions that were previously under discussion. It has been postulated that Helicobacter pylori infection always causes gastritis, regardless of symptoms or complications. Before making a convincing diagnosis of functional dyspepsia, it is necessary to exclude Helicobacter’s gastritis. Some provisions of the consensus, such as the “test and treat” tactic, require elements of a critical attitude, taking into account Russian regional conditions. About 90% of stomach cancers are due to H. pylori. Eradication of H. pylori makes it possible to prevent gastric cancer at any age in adulthood, but the effectiveness of such cancer prevention decreases with age. Bismuth quadruple therapy is preferred in the eradication therapy algorithm. Decreased value of triple treatment with clarithromycin. There is a rapid increase in H. pylori resistance to fluoroquinolones. Triple therapy with rifabutin is called the final eradication protocol.
Keywords: Helicobacter pylori, proton pump inhibitors, eradication, triple therapy, bismuth quadruple therapy, resistance to antibiotics, antimicrobial drugs
First page
352
Last page
356
For citation:Zakhidova M.Z. - ONCE AGAIN ABOUT HELICOBACTERIA: RECOMMENDATIONS OF THE MAASTRICHT VI/FLORENCE CONSENSUS ON THE TREATMENT OF HELICOBACTER PYLORI INFECTION//New Day in Medicine 12(74)2024 352-356 https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024
List of References
- Ивашкин В.Т., Маев И.В., Лапина Т.Л, и др. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению инфекции Helicobacter pylori у взрослых. Российский журнал гастроэнтерологии, гепатологии и колопроктологии. 2018;28(1):55-70 [Ivashkin VT, Mayev IV, Lapina TL, et al. Diagnostics and treatment of Helicobacter pylori infection in adults: Clinical guidelines of the Russian gastroenterological association. Russian Journal of Gastroenterology, Hepatology and Coloproctology. 2018;28(1):55-70
- Malfertheiner P, Megraud F, Rokkas T, et al. Management of Helicobacter pylori infection: the Maastricht VI/ Florence consensus report. Gut. 2022;71(9):1724-62.
- Wauters L, Dickman R, Drug V, et al. United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia. United European Gastroenterol J. 2021;9(3):307-31. DOI:10.1002/ueg2.12061
- Ивашкин В.Т., Маев И.В., Лапина Т.Л., и др. Клинические рекомендации Российской гастроэнтерологической ассоциации и ассоциации «Эндоскопическое общество РЭНДО» по диагностике и лечению гастрита, дуоденита. Российский журнал гастроэнтерологии, гепатологии и колопроктологии. 2021;31(4):70-9 [Ivashkin VT, Maev IV, Lapina TL, et al. Clinical Recommendations of Russian Gastroenterological Association and RENDO Endoscopic Society on Diagnosis and Treatment of Gastritis and Duodenitis. Russian Journal of Gastroenterology, Hepatology and Coloproctology. 2021;31(4):70-99 (in Russian)]. DOI:10.22416/1382-4376-2021-31-4-70-99
- Ивашкин В.Т., Маев И.В., Трухманов А.С., и др. Воспаление, нарушение моторной функции и висцеральная гиперчувствительность: основные механизмы функциональных расстройств желудочно-кишечного тракта (обзор литературы и резолюция Совета Экспертов). Российский журнал гастроэнтерологии, гепатологии и колопроктологии. 2022;32(1):7-14 [Ivashkin VT, Maev IV, Trukhmanov AS, et al. Inflammation, impaired motor function and visceral hypersensitivity: the main mechanisms of functional disorders of the gastrointestinal tract (materials of the Expert Council and literature review). Russian Journal of Gastroenterology, Hepatology and Coloproctology. 2022;32(1):7-14 (in Russian)]. DOI:10.22416/1382-4376-2022-32-1-7-14
- Milanović V, Osimani A, Cardinali F, et al. Erythromycin-resistant lactic acid bacteria in the healthy gut of vegans, ovo-lacto vegetarians and omnivores. PLoS One. 2019;14(8):e0220549. DOI:10.1371/journal.pone.0220549
- Zhang M, Zhang C, Zhao J, et al. Meta-analysis of the efficacy of probiotic-supplemented therapy on the eradication of H. pylori and incidence of therapy-associated side effects. Microb Pathog. 2020;147:104403. DOI:10.1016/j.micpath.2020.104403
file
download