73 -12 (74) 2024 - Amonov M.K. - OVERWEIGHT AND RENAL FUNCTION

OVERWEIGHT AND RENAL FUNCTION

Amonov M.K. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Increasing evidence accumulate to suggest that overweight increases the risk of chronic kidney disease independently of dyslipidemia, diabetes, and hypertension. This so-called overweight-related glomerulopathy is characterized at early stages by glomerular hypertrophy with or without secondary focal segmental glomerulosclerosis. Since, however, kidney biopsies are usually not performed at this phase, an early diagnosis of the disease is often difficult. Here, we review new developments in the pathophysiology of overweight-associated kidney dysfunction and discuss the potential of appropriate monitoring of glomerular filtration rate and albuminuria for early detection of the disease. We also present the benefits conferred by even moderate dietary restriction on the course of the disease.

Key words: overweight-related glomerulopathy, overweight, albuminuria, glomerular filtration rate, dietary restriction, glomerular sclerosis

First page

374

Last page

379

For citation:Amonov M.K. - OVERWEIGHT AND RENAL FUNCTION//New Day in Medicine 12(74)2024 374-379 https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024

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