116 -12 (74) 2024 - Shomurodova M.R. - RESULTS OF THE STUDY OF MORPHOLOGICAL CHANGES IN THE LUNGS CAUSED BY CHEMOTHERAPY USING THE IMMUNOHISTOCHEMICAL MARKER Ki-67
RESULTS OF THE STUDY OF MORPHOLOGICAL CHANGES IN THE LUNGS CAUSED BY CHEMOTHERAPY USING THE IMMUNOHISTOCHEMICAL MARKER Ki-67
Shomurodova M.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina
Resume
In recent years, the incidence of breast cancer and death from this disease have increased dramatically around the world. In this study, morphological changes in the lungs of white rats with experimental mammary gland cancer were investigated by immunohistochemical method. Micropreparations prepared from lung tissue structures isolated from them were examined with immunohistochemical marker Ki-67 and the results were presented depending on the level of expression of this marker.
Key words: Ki-67 marker, Breast cancer, cell proliferation, proliferation index, immunohistochemical analysis, lung.
First page
605
Last page
609
For citation:Shomurodova M.R. - RESULTS OF THE STUDY OF MORPHOLOGICAL CHANGES IN THE LUNGS CAUSED BY CHEMOTHERAPY USING THE IMMUNOHISTOCHEMICAL MARKER Ki-67//New Day in Medicine 12(74)2024 605-609 https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024
List of References
- Shomurodova Mukhayo Rakhmonovna, (May 6, 2023). Morphological Features and Morphometric Parameters of the Lungs after Correction with an Immunomodulator Under the Conditions of Experimental Chemotherapy. //Journal of Natural and Medical Education 2023;5:(55-60).
- Shomurodova Mukhayo Rakhmonovna, (2023) Mastopatiya. Yosh Patmorfolog Nigohida. //Amaliy va tibbiyot fanlari ilmiy jurnali 2023;5193-197) https://sciencebox.uz
- Shomurodova Muxayyo Raxmonovna (2023) Morfometricheskie Pokazateli Legkix Posle Korreksii Immunomodulyatorom V Usloviyax Eksperimentalnoy Ximioterapii //Amaliy va tibbiyot fanlari ilmiy jurnali 2023;5:(198-202) https://sciencebox.uz
- Shomurodova M.R. (2023). Morphological Changes in Lungs Caused by Chemotherapy in Breast Cancer. //American Journal of Pediatric Medicine and Health Sciences (2993-2149), 2023;1(10):341-344. Retrieved from http://grnjournal.us/index.php/AJPMHS/article/view/2088
- Volchenko N.N., Frank G.A. Kompleks morfologicheskix i prognosticheskix faktorov pri rake molochnoy jelezы: Posobie dlya vrachey. M., 2000.
- Immunogistoximicheskie metodi: Rukovodstvo. Per. s angl. pod red. G.A. Franka i P.G. Malkova /M., 2011; 224 st.
- Pojarisskiy M., Leenman Ye.N. Znachenie immunogistoximicheskix metodik dlya opredeleniya xaraktera lecheniya i prognoza opuxolevыx zabolevaniy //Arx. patol., 2000;(5):3-11.
- Schmitt S.A., Love S.W. Apoptosis and therapy. G. Path., 1999;187:127-37.
- Viale G., Regan M.M., Mastropasqua M.G. et al. Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer //J. Natl sancer Inst. 2009;100(3):207-212.
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