125 -12 (74) 2024 - Makhmudova L.I., Abdullaev I.A. - IMPORTANCE OF GUT MICROBIOTA ANALYSIS IN ASSESSING CLINICAL-LABORATORY SEVERITY LEVELS OF INTESTINAL IRRITATION SYNDROME

IMPORTANCE OF GUT MICROBIOTA ANALYSIS IN ASSESSING CLINICAL-LABORATORY SEVERITY LEVELS OF INTESTINAL IRRITATION SYNDROME

Makhmudova L.I. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Abdullaev I.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The study was carried out in the Polyclinic and gastroenterology department of the Bukhara regional Multidisciplinary Medical Center, and 90 patients were selected who were examined in an outpatient setting with irritable bowel syndrome (IBS). Patients with IBS were divided into two groups: the diarrheal-dominant type of its (IDS – D-43 patients) and the constipation – dominant type (IBS-C-43 patients). Gut microbiota analysis on its weight levels showed that moderate to severe patients with mild levels had normal enzymatic activity and a decrease in lactozonegative bacteria was noted. From conditionally pathogenic Enterobacteria-E. Coli levels have been observed to increase at moderate to severe levels of IBS, from staphylococci to St. Aureus was only identified in patients with severe levels of IBS. Bifidobacteria and lactobacilli, which are considered beneficial bacteria, were noted in patients with moderate to severe IBS levels.

Keywords: irritable bowel syndrome, intestinal symptoms, intestinal microbiota, intestinal dysbiosis

First page

659

Last page

663

For citation:Makhmudova L.I., Abdullaev I.A. - IMPORTANCE OF GUT MICROBIOTA ANALYSIS IN ASSESSING CLINICAL-LABORATORY SEVERITY LEVELS OF INTESTINAL IRRITATION SYNDROME//New Day in Medicine 12(74)2024 659-663 https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024

List of References

1. Abdullayev RB, Makhmudova LI Features of Chemical Elements in Various Forms of Irritable Bowel Syndrome // Annals of RSCB, ISSN:1583-6258, 2021;25(2):2993 - 3000.
2. Abdullayev R.B., Makhmudova L.I., (2021). Assessment Of Clinical And Psychological Status And Quality Of Life Of Patients In Different Forms Of Irritable Bowel Syndrome. The American Journal of Medical Sciences and Pharmaceutical Research, 2021;3(2):127-134.
3. Makhmudova LI, Akhmedova N.Sh., Ergashov BB Clinical manifestation of irritable bowel syndrome. Art of medicine. International medical scientific journal. 2021;1(2):24-33.
4. Mayev I.V., Cheremushkin S.V., Curly Yu.A. Irritable bowel syndrome. Roman Criteria IV. On the role of visceral hypersensitivity and ways to correct it. Methodical manual. M., 2016.
5. Mayev I.V., Cheremushkin S.V., Kucheryavy Yu.A., Cheremushkina N.V. irritable bowel syndrome. Roman Criteria IV. Consilium Medicum. 2016;18(8):79-85.
6. Hanyukov A.A., Fedorova N.S. Possibilities and prospects in the diagnosis of functional pathology of the intestine. //About the child's health. – Ukraine, 2017;12(2.1):57-61.
7. Sheptulin A.A., Vize-Khripunova M.A. New in the etiology and pathogenesis of irritable bowel syndrome. //Clinical medicine. 2016;94(2):92-96.

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