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  • 147 -12 (74) 2024 - Khalilova K.O., Abdurakhmanova S.I. - THE ROLE OF THE CULTURE MEDIUM WITH HYALURONIC ACID AT THE ONSET OF PREGNANCY AFTER THE TRANSFER OF EUPLOID EMBRYOS

147 -12 (74) 2024 - Khalilova K.O., Abdurakhmanova S.I. - THE ROLE OF THE CULTURE MEDIUM WITH HYALURONIC ACID AT THE ONSET OF PREGNANCY AFTER THE TRANSFER OF EUPLOID EMBRYOS

THE ROLE OF THE CULTURE MEDIUM WITH HYALURONIC ACID AT THE ONSET OF PREGNANCY AFTER THE TRANSFER OF EUPLOID EMBRYOS

Khalilova K.O. - Israel Medical Center for Human Reproduction and Family Health, Tashkent, Uzbekistan

Abdurakhmanova S.I. - The Department of Obstetrics and Gynecology of the Tashkent State Dental Institute

Boboev S.G. - The Department of Genetics of the National University of Uzbekistan

Resume

To improve the results of assisted reproductive technologies (ART) in patients with infertility, adhesive compounds such as hyaluronic acid (HA) are used.Adhesive compounds are added to the medium used during embryo transfer to increase the likelihood of embryo implantation, potentially leading to higher clinical pregnancy and live birth rates.

Key words: assisted reproductive technologies, media with hyaluronic acid, embryo transfer.

First page

776

Last page

779

For citation:Khalilova K.O., Abdurakhmanova S.I., Boboev S.G. - THE ROLE OF THE CULTURE MEDIUM WITH HYALURONIC ACID AT THE ONSET OF PREGNANCY AFTER THE TRANSFER OF EUPLOID EMBRYOS//New Day in Medicine 12(74)2024 776-779 - https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024

List of References

  1. Urman et al. (2008) Effect of hyaluronan-enriched transfer medium on implantation and pregnancy rates after day 3 and day 5 embryo transfer: a prospective randomized study. //Fert Steril 2008;90(3):604-12.
  2. Bontekoe S et al. (2010) Cochrane Database Syst Rev. 2010 Jul 7;(7):CD007421.
  3. Bontekoe S et al., (2014) Cochrane Database Syst Rev. Feb 25;2:CD007421.
  4. Balaban B et al. (2011) Effect of hyaluronan-enriched transfer medium on take home baby rate after day 3 and day 5 embryo transfers: a prospective randomized study. Hum Reprod. July 15(15):i24.
  5. Hashimoto S et al. (2014) EmbryoGlue improvespregnancy and implantation rates: Results from a Metaanalysis on almost 10,000 embryo transfers. //Reprod BioMed Online. 2014;28(Suppl 1):S7-S8.
  6. Meintjes M (2012) Media composition; macromolecules and embryo growth. //Methods Mol Biol. 2012;912:107-27.
  7. Morbeck et al. (2014) Composition of protein supplements used for human embryo culture. //J Assist Reprod Genet. 2014;12:1703-11.
  8. Blake et al. (2002) Protein Supplementation of human IVF culture media. J Assist Reprod Genet. 2002;19:137-43.
  9. Leonard et al. (2013) Variability in protein quality used for embryo culture: embryotoxicicity of the stabilizer octanoic acid. //Fertil Steril. 2013;100:544-549.
  10. Lane et al. (2003) Cryo-survival and development of bovine blastocysts are enhanced by culture with recombnant albumin and hyaluronan. //Mol Reprod Dev 2003;64:70-78.

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