165 -12 (74) 2024 - Sanoev B.A., Kaimanova K.I. - MORPHOLOGICAL CHANGES IN THE KIDNEY IN EXPERIMENTAL ULCERATIVE COLITIS

MORPHOLOGICAL CHANGES IN THE KIDNEY IN EXPERIMENTAL ULCERATIVE COLITIS

Sanoev B.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Kaimanova K.I. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Histological analysis of kidney tissue from 9-month-old white rats with ulcerative colitis revealed accumulation of glycosaminoglycans in the mesangial cells and matrix of the glomeruli, thickening of the basement membrane due to the accumulation of acid mucopolysaccharides, changes in the glomeruli as a result of exudative processes, an increase in mucopolysaccharides in the epithelial cells of the tubules, and accumulation of lymphocytes, plasma cells, and macrophages in the interstitial space. Morphological changes in the kidneys in ulcerative colitis may be associated with several factors, including autoimmune reactions and inflammation.

Keywords: kidney, ulcerative colitis, morphology, histochemical analysis, alcian blue stain.

First page

863

Last page

867

For citation:Sanoev B.A., Kaimanova K.I. - MORPHOLOGICAL CHANGES IN THE KIDNEY IN EXPERIMENTAL ULCERATIVE COLITIS//New Day in Medicine 12(74)2024 863-867 https://https://newdayworldmedicine.com/en/new_day_medicine/12-74-2024

List of References

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  2. Honap S. et al. Acute Severe Ulcerative Colitis: An International Delphi Consensus on Clinical Trial Design and Endpoints //Clinical Gastroenterology and Hepatology. 2024.
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