1 -1 (75) 2025 - Mustafaeva M.R. - CLINICAL AND LABORATORY ASPECTS OF PREDICTING THE DEVELOPMENT OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH CONTRAST-INDUCED NEPHROPATHY

CLINICAL AND LABORATORY ASPECTS OF PREDICTING THE DEVELOPMENT OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH CONTRAST-INDUCED NEPHROPATHY

Mustafaeva M.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Contrast-induced chronic kidney injury (CI-CKI) is the chronic impairment of renal function further to the intravascular administration of iodinated contrast media, and occurs most frequently after coronary angiography, percutaneous coronary intervention, and contrast-enhanced computed tomography. CI-CKI has been associated with the development of chronic renal failure, worsening of chronic kidney disease, requirement for dialysis, prolonged hospital stay, and higher mortality rates and health care costs. Recently, a number of studies suggested that contrast media exposure might not be the causative agent in the occurrence of chronic kidney injury, particularly in stable patients who receive small to moderate amounts of contrast media. However, those who undergo coronary angiography and intervention are indeed subject to an increased hazard of CI-CKI, in view of a more significant contrast media exposure as well as the presence of concomitant risk factors. Solid randomized clinical trials are therefore required to identify preventative strategies to reduce the risk of CI-CKI and its complications in these patients.

Key words: chronic kidney disease, contrast-induced nephropathy, percutaneous coronary intervention

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For citation:Mustafaeva M.R. - CLINICAL AND LABORATORY ASPECTS OF PREDICTING THE DEVELOPMENT OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH CONTRAST-INDUCED NEPHROPATHY//New Day in Medicine 1(75)2025 2-6 https://https://newdayworldmedicine.com/en/new_day_medicine/1-75-2025

List of References

1. Sharipovna A.N., Bakhodirovich E.B., Otaevna N.H., Avazkhonovna S.G. (2021) Analysis of the results of a study on the frequency of occurrence and prevelance of risk factors for chronic disease. //International Journal of Current Research and Review, 2021;13(2):127-131. doi10.31782/IJCRR.2021.13232
2. Олимова Г.Ш. Determination of early risk factors for chronic kidney disease in adolescents. /Олимова Г.Ш. //Asian journal of Pharmateutical and biological research. 2020;12(2.3):9. https://ajpbr.org/index.
3. Azzalini L, Spagnoli V, Ly HQ. Contrast-Induced nephropathy: from pathophysiology to preventive strategies. //Can J Cardiol 2015;32:247-55.
4. Aspects of prediction of chronic kidney disease in outpatient conditions. Akhmedova nilufar sharipovna, ravshanov sardor sharipovich //Elektronniy nauchniy jurnal “Biologiya i integrativnaya meditsina” 2022;2(55).
5. Azzalini L, Garcia-Moll X. On contrast-induced chronic kidney injury, risk prediction, and the future of predictive model development. //Can J Cardiol 2017;33:711-3.
6. Wilhelm-Leen E, Montez-Rath ME, Chertow G. Estimating the risk of radiocontrast-associated nephropathy. //J Am Soc Nephrol 2017;28:653-9.
7. Inohara T, Kohsaka S, Miyata H, et al. Performance and validation of the U.S. NCDR chronic kidney injury prediction model in Japan. //J Am Coll Cardiol 2016;67:1715-22.
8. Andò G, Cortese B, Russo F, et al. Chronic kidney injury after radial or femoral access for invasive chronic coronary syndrome management: CKI- MATRIX. //J Am Coll Cardiol 2017;69:2592-603.
9. Ozturk D, Celik O, Erturk M, et al. Utility of the logistic clinical Syntax score in the prediction of contrast-induced nephropathy after primary percutaneous coronary intervention. //Can J Cardiol 2016;32:240-6.
10. Nijssen EC, Rennenberg RJ, Nelemans PJ, et al. Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. //Lancet 2017;389:1312-22.

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