69 -1 (75) 2025 - Oripova Sh.A., Sadiev E.S. - EVALUATION OF THE EXPRESSION LEVELS OF IMMUNOHISTOCHEMICAL MARKERS BCL-2, KI-67, AND VEGFR IN SECONDARY PLACENTAL INSUFFICIENCY

EVALUATION OF THE EXPRESSION LEVELS OF IMMUNOHISTOCHEMICAL MARKERS BCL-2, KI-67, AND VEGFR IN SECONDARY PLACENTAL INSUFFICIENCY

Oripova Sh.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Sadiev E.S. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

In secondary placental insufficiency, inflammatory processes are often morphologically detected in placental tissue, each manifesting with specific changes. Placental insufficiency is a syndrome based on morphofunctional changes in the placenta, which, when progressing, leads to delayed fetal growth and the development of hypoxia. Therefore, improving the diagnosis of various forms of placental insufficiency during pregnancy is one of the important issues in modern morphology. Immunohistochemical (IHC) analysis is a crucial diagnostic and research method in modern medicine and biology. Studies aimed at assessing the expression levels of immunohistochemical markers such as Ki-67 and Bcl-2, VEGFR as well as the comparative analysis of morphometric indicators of tissue structures in histological forms of placental tissue in secondary placental insufficiency, hold significant scientific and practical importance.

Key words: Secondary placental insufficiency, placental villi, uterus, Immunohistochemical markers, morphology, morphometry.

First page

403

Last page

409

For citation:Oripova Sh.A., Sadiev E.S. - EVALUATION OF THE EXPRESSION LEVELS OF IMMUNOHISTOCHEMICAL MARKERS BCL-2, KI-67, AND VEGFR IN SECONDARY PLACENTAL INSUFFICIENCY//New Day in Medicine 1(75)2025 403-409 https://https://newdayworldmedicine.com/en/new_day_medicine/1-75-2025

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