71 -1 (75) 2025 - Olimova D.V., Habibova N.N. - BIOCHEMICAL ANALYSIS OF SALIVA AND CHANGES IN SALIVARY pH IN PATIENTS WITH CHRONIC KIDNEY DISEASE UNDERGOING HEMODIALYSIS

BIOCHEMICAL ANALYSIS OF SALIVA AND CHANGES IN SALIVARY pH IN PATIENTS WITH CHRONIC KIDNEY DISEASE UNDERGOING HEMODIALYSIS

Olimova D.V. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Habibova N.N. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Chronic kidney disease (CKD) is a progressive condition that has far-reaching impacts on systemic health, including significant alterations in oral physiology. Among patients undergoing hemodialysis, changes in salivary biochemistry and pH are pronounced, reflecting systemic metabolic imbalances and influencing oral health outcomes. This article reviews the biochemical parameters of saliva, such as elevated levels of urea, creatinine, inflammatory markers, and oxidative stress compounds, in the context of CKD. Additionally, it explores the implications of altered salivary pH on microbial ecology and dental health, emphasizing the need for integrated oral care within CKD management. These findings underscore the importance of interdisciplinary approaches to enhance quality of life for CKD patients.

Keywords: chronic kidney disease, hemodialysis, saliva biochemistry, salivary pH, oxidative stress, oral health

First page

415

Last page

418

For citation:Olimova D.V., Habibova N.N. - BIOCHEMICAL ANALYSIS OF SALIVA AND CHANGES IN SALIVARY pH IN PATIENTS WITH CHRONIC KIDNEY DISEASE UNDERGOING HEMODIALYSIS//New Day in Medicine 1(75)2025 415-418 https://https://newdayworldmedicine.com/en/new_day_medicine/1-75-2025

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