7 -2 (76) 2025 - Musashaykhov Х.Т., Nazarov I.R. - DEVELOPMENT OF EFFECTIVE CRITERIA FOR PREDICTING THE RISK OF DEVELOPMENT OF LOWER LEGS HEPATIC-NECROTIC LESIONS IN DIABETIC PATIENTS, TAKING INTO ACCOUNT THE MOLECULAR-GENETIC ASPECTS

DEVELOPMENT OF EFFECTIVE CRITERIA FOR PREDICTING THE RISK OF DEVELOPMENT OF LOWER LEGS HEPATIC-NECROTIC LESIONS IN DIABETIC PATIENTS, TAKING INTO ACCOUNT THE MOLECULAR-GENETIC ASPECTS

Musashaykhov Х.Т. - Andijan State Medical Institute

Nazarov I.R. - Andijan State Medical Institute

Musashaykhov U.Kh. - Andijan State Medical Institute

Resume

Analysis results showed that the frequency of deletion of the genetic marker GSTM1 in the main group of patients was 3.7 times higher than in the control group (χ2=15.6; P=0.01; OR=3.7; 95% CI: 1.93-7 Molecular-genetic studies of our clinical material were conducted in the departments of molecular medicine and cell technology, as well as in the laboratory of medical genetics of the Republican Specialized Scientific and Practical Medical Center of Hematology of the Ministry of Health of the Republic of Uzbekistan.

Key words: GSTM1, diabetes mellitus, lower extremity diseases, molecular genetics, PCR, surgery.

First page

34

Last page

38

For citation:Musashaykhov Х.Т., Nazarov I.R., Musashaykhov U.Kh. - DEVELOPMENT OF EFFECTIVE CRITERIA FOR PREDICTING THE RISK OF DEVELOPMENT OF LOWER LEGS HEPATIC-NECROTIC LESIONS IN DIABETIC PATIENTS, TAKING INTO ACCOUNT THE MOLECULAR-GENETIC ASPECTS//New Day in Medicine 2(76)2025 34-38 https://https://newdayworldmedicine.com/en/new_day_medicine/2-75-2025

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