8 -2 (76) 2025 - Khaidarova S.H., Mavlyanova Z.F. - SPECTRUM OF SENSITIZATION IN CHILDREN WITH BRONCHIAL ASTHMA AND CONSEQUENCES OF PERINATAL CENTRAL NERVOUS SYSTEM DAMAGE

SPECTRUM OF SENSITIZATION IN CHILDREN WITH BRONCHIAL ASTHMA AND CONSEQUENCES OF PERINATAL CENTRAL NERVOUS SYSTEM DAMAGE

Khaidarova S.H. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Mavlyanova Z.F. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Butabaev M.T. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The aim of the study was to evaluate the features of sensitization in children with bronchial asthma in children who have suffered perinatal pathology of the central nervous system. Material and methods of the study: a comprehensive examination of 221 children suffering from bronchial asthma was conducted. The average age of the examined children was 11.4 ± 2.9 years. Results of the study: an in-depth allergen-specific analysis of children with bronchial asthma was carried out in two observation groups: the main group (114 children with bronchial asthma with concomitant neurological symptoms) and the comparison group (107 neurologically healthy children with a similar disease). A reliable difference in the level of total IgE was found in children of the main group and the comparison group, on average 1.3 times higher in children with bronchial asthma against the background of remote consequences of perinatal damage to the central nervous system.

Key words: bronchial asthma, consequences, perinatal damage, central nervous system, atopy, immunoglobulin E.

First page

39

Last page

45

For citation:Khaidarova S.H., Mavlyanova Z.F., Butabaev M.T. - SPECTRUM OF SENSITIZATION IN CHILDREN WITH BRONCHIAL ASTHMA AND CONSEQUENCES OF PERINATAL CENTRAL NERVOUS SYSTEM DAMAGE//New Day in Medicine 2(76)2025 39-45 https://https://newdayworldmedicine.com/en/new_day_medicine/2-75-2025

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