16 -6 (38) 2021 — Safarova Gulnoz Avazkhanovna — FEATURES OF THE CLINICAL COURSE OF COVID-19 IN COMORBID CONDITIONS

FEATURES OF THE CLINICAL COURSE OF COVID-19 IN COMORBID CONDITIONS

Safarova Gulnoz Avazkhanovna Bukhara state medical institute

Resume

The 2019 Coronavirus Disease (COVID-19) pandemic is a rapidly evolving global emergency that continues to place pressure on health systems. New studies are describing many factors that affect the patient, including demographic, clinical, immunologic, hematologic, biochemical, and radiologic data, that can be useful to clinicians in predicting COVID-19 severity and mortality. We present the results of a study of current scientific information related to the factors predicting the clinical course and outcome of COVID-19. Hypothesis-driven research is critical to identifying key evidence-based predictors that will inform the design of interventional research to improve treatment outcomes for COVID-19 patients and appropriately allocate scarce resources.

Key words: COVID-19, comorbidity, SARS-CoV-2, clinical course

First page

88

Last page

95

For citation: Safarova Gulnoz Avazkhanovna FEATURES OF THE CLINICAL COURSE OF COVID-19 IN COMORBID CONDITIONS //New Day in Medicine 6(38)2021 88-95 https://cutt.ly/8Yy6PCK

LIST OF REFERENCES:

  1. Akhmedova N.Sh., Ergashov B.B.,  Nuralieva H.O., Safarova G.A. Influence of Collected Modified Risk Factors on the Development and Progression of Chronic Kidney Disease// International Journal of Current Research and Review  Vol 13 • Issue 02 • January 2021 Pagts 13-
  2. Gondi S, Beckman AL, Deveau N, et al. Personal protective equipment needs in the USA during the COVID-19 pandemic. Lancet. 2020;395(10237):e90 https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7255297/.
  3. Guan W-J, Ni Z-Y, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708. https://doi. org/10.1056/NEJMoa2002032.
  4. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395 (10223):497-506. https://doi.org/10.1016/S0140-6736(20)30183-5.
  5. Li X, Xu S, Yu M, et al. Факторы риска тяжести и смертности взрослых пациентов с COVID-19 в Ухани. J Allergy Clin Immunol. 2020; 146: 110. https://doi.org/10.1016/j.jaci.2020.04.006.
  6. Makhmudov R.B., Safarova G.A., (2021). Clinical Cases Of Hepatitis-Associated Aplastic Anemia. The American Journal of Medical Sciences and Pharmaceutical Research, 3(04), 195-199.   Doi: https://doi.org/10.37547/TAJMSPR/ Volume03Issue04-28
  7. Mani VR, Kalabin A, Valdivieso SC, Murray-Ramcharan M, Donaldson B. At the epicenter of the American coronavirus outbreak – New York inner city hospital COVID-19 experience and current data: a retrospective analysis. J Med Internet Res. 2020. https://doi. org/10.2196/20548.
  8. Safarova G.A. Vasorenal hemodynamic changes in patients with chronic kidney disease in comorbidity with hypertonic disease. Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/    Volume 10. Issue 2. MAY-AUG 2021 10.5281/zenodo.5464135 Page  66-71
  9. Safarova G.A., Mukhamedjanova M.Kh., Ubaydova D.S.  Features of the indices of the resistance index of vasorenal vessels in monitoring the progression of chronic kidney disease. Asian journal of Pharmaceutical and biological research 2231-2218 http://www.ajpbr.org/ Volume 10. Issue 2. MAY-AUG 2021. 10.5281/zenodo.5519192 Pages 78-84
  10. SOHIBOVA Z.R., SAFAROVA G.A. MODERN CONCEPTS ABOUT THE VALUE OF MACRO- AND MICROELEMENTS IN PHYSIOLOGY AND PATHOLOGY OF THE BODY ( REVIEW). Journal of Biomedicine and Practice 2020, vol.6, issue 5, pp.238-243 http://dx.doi.org/10.26739/2181-9300-2020-6-38
  11. Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323:1061. https://doi.org/10.1001/jama.2020.1585.
  12. WHO. Clinical Management of COVID-19: Interim Guidance, 27 May 2020. World Health Organization; 2020. https://apps.who. int/iris/bitstream/handle/10665/332196/WHO-2019-nCoVclinical-2020.5-eng.pdf
  13. Zhang L, Jackson CB, Mou H, et al. The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity. bioRxiv. June 2020. doi:https://doi.org/10.1101/2020.06.12.148726
  14. Zhang X, Tan Y, Ling Y, et al. Viral and host factors related to the clinical outcome of COVID-19. Nature. 2020. https://doi.org/10. 1038/s41586-020-2355-0.
  15. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054. https://doi.org/10.1016/S0140-6736(20)30566-3.
  16. Mukhamedzhanova M.KH., Safarova G.A. OTSENKA VAZORENAL’NOY GEMODINAMIKI U BOL’NYKH S KHRONICHESKOY BOLEZN’YU POCHEK V ASSOTSIATSII S ARTERIAL’NOY GIPERTENZIYEY. Problemy biologii i meditsiny 2020, №6 (124) 87-90 str. UDK: 616.1+615.2.03+613.1
  17. Mukhammedzhanova M.KH. ANEMIYA U PATSIYENTOV S ZABOLEVANIYAMI PECHENI: PATOGENETICHESKIYe OSOBENNOSTI I VOZMOZHNOSTI TERAPII. Novyy den’ v meditsine 4(36)2021   pages 150-153. ISSN 2181-712X. EISSN 2181-2187
  18. Paleodimos L., Kokkinidis D.G., Li V. i dr. Tyazheloye ozhireniye, uvelicheniye vozrasta i muzhskogo pola nezavisimo drug ot druga svyazany s khudshimi iskhodami v bol’nitse i boleye vysokoy vnutribol’nichnoy smertnost’yu v kogorte patsiyentov s COVID-19 v Bronkse, N’yu-York. Obmen veshchestv. 2020; 108: 154262. https://doi.org/10.1016/j.metabol.2020.154262.

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