53 -2 (76) 2025 - Nuriddinov A.M. - MORPHO-FUNCTIONAL PROPERTIES OF THE KIDNEY TISSUE OF WHITE-BLOODED MICE IN EXPERIMENTAL COMPOUND INJURIES

MORPHO-FUNCTIONAL PROPERTIES OF THE KIDNEY TISSUE OF WHITE-BLOODED MICE IN EXPERIMENTAL COMPOUND INJURIES

Nuriddinov A.M. - Bukhara State Medical Institute named after Abu Ali ibn Sino

Resume

Kidney diseases caused by compound injuries are one of the urgent problems of modern urology and nephrology. Based on the analysis of the data obtained through histochemical studies, the accumulation of acidic mucopolysaccharides in the intracellular and extracellular matrix when stained with alcian blue indicates that hypoxia and accumulation of intermediates continue. Depending on the duration of the process, these changes, if the process is stopped, end with poorly formed fibrosis or poorly formed sclerotic changes in the renal parenchyma, which is clinically and morphologically manifested by mild to moderate acute renal failure. Histologically, histomorphometric and biochemical indicators confirmed the pronounced changes in the nephron elements of the 3-month-old white crossbred rats of the experimental group, which were injured by experimental joint injury for 3 days.

Keywords: Joint injuries, kidney, nephron, immunohistochemical markers, morphology, morphometry.

First page

280

Last page

286

For citation:Nuriddinov A.M. - MORPHO-FUNCTIONAL PROPERTIES OF THE KIDNEY TISSUE OF WHITE-BLOODED MICE IN EXPERIMENTAL COMPOUND INJURIES//New Day in Medicine 2(76)2025 280-286 https://https://newdayworldmedicine.com/en/new_day_medicine/2-76-2025

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