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87 -3 (77) 2025 - Xolova N.F., Nasriddinova K.P. - THE CONCEPT OF TORCH INFECTIONS, ASPECTS OF REPRODUCTIVE LOSSES: DATA ANALYSIS

THE CONCEPT OF TORCH INFECTIONS, ASPECTS OF REPRODUCTIVE LOSSES: DATA ANALYSIS

Xolova N.F. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Nasriddinova K.P. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Yakubova O.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Resume

The term TORCH is used to denote the most common perinatal infections, where: (T) refers to toxoplasmosis, (O) means "other" and includes syphilis, chickenpox, parvovirus B19, Zika virus (ZIKV) and malaria among others, (R) refers to rubella, (C) refers to cytomegalovirus infection and (H) to herpes simplex virus infections. Among the major abnormalities found in neonates exposed to congenital infections are central nervous system (CNS) involvement, microcephaly, hearing loss, and ophthalmologic abnormalities, all of which require regular follow-up to monitor their progression. Protein changes such as mutations, post-translational modifications, abundance, structure, and function can indicate a pathological condition before symptoms appear, allowing for early diagnosis and understanding of a specific disease or infection.

Keywords: TORCH infections, pregnancy, congenital anomalies, spectrometry.

First page

498

Last page

505

For citation:Xolova N.F., Nasriddinova K.P., Yakubova O.A. - THE CONCEPT OF TORCH INFECTIONS, ASPECTS OF REPRODUCTIVE LOSSES: DATA ANALYSIS//New Day in Medicine 3(77)2025 498-505 https://https://newdayworldmedicine.com/en/new_day_medicine/3-77-2025

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