124 -3 (77) 2025 - Mavlyanova Sh.Z., Mirsaidova U.A. - ON THE ISSUE OF METABOLIC SYNDROME IN PATIENTS WITH PSORIASIS

ON THE ISSUE OF METABOLIC SYNDROME IN PATIENTS WITH PSORIASIS

Mavlyanova Sh.Z. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan

Mirsaidova U.A. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan

Ismagilov A.I. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan

Resume

The study of metabolic syndrome within the dermatological discipline is a priority in terms of developing pathogenetic treatment methods for chronic skin diseases Aim of the study: to investigate the comorbid conditions in patients with psoriasis, taking into account the age and sex of the patients. Materials and methods: We examined 210 patients with psoriasis, aged from 2.5 to 67 years. All patients underwent clinical, laboratory (general clinical, biochemical), functional (ultrasound), and statistical studies, as well as consultations with related specialists. Results: The PASI severity score assessment revealed mild severity in 76 (36.2%) patients, moderate severity in 102 (48.6%) patients, and severe severity in 32 (15.2%) patients. Clinical and laboratory results in patients with psoriasis showed metabolic syndrome with endocrine disorders in 81 (38.6%). Considering the clinical course, in the group of patients with mild PASI, normal body mass index (BMI) values were recorded in 59.2% of men and 74.7% of women. In moderate to severe psoriasis, there was a decrease in the proportion of patients with normal BMI values - 39.3% in men and 28.2% in women. This indicates a progressive shift towards overweight or obesity with increasing severity of the psoriatic process. In the group of patients with severe psoriasis, normal BMI was found in only 10.3% of men. Conclusion: Thus, the results of the study indicate the need for a comprehensive approach to social responsibility and lifestyle and metabolic correction in patients with psoriasis, especially in moderate to severe cases.

Key words: psoriasis, clinical, PASI (Psoriasis Area and Severity Index), metabolic syndrome, obesity, body mass index (BMI)

First page

707

Last page

713

For citation:Mavlyanova Sh.Z., Mirsaidova U.A., Ismagilov A.I. - ON THE ISSUE OF METABOLIC SYNDROME IN PATIENTS WITH PSORIASIS//New Day in Medicine 3(77)2025 707-713 https://https://newdayworldmedicine.com/en/new_day_medicine/3-77-2025

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