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39 -6 (38) 2021 — Giyosova Nigora Odiljonovna — BASIC MOMENTS OF KIDNEY DAMAGE IN COVID-19 IN PATIENTS WITH COMORBID DISEASES

BASIC MOMENTS OF KIDNEY DAMAGE IN COVID-19 IN PATIENTS WITH COMORBID DISEASES

Giyosova Nigora Odiljonovna Bukhara state medical institute, Bukhara, Uzbekistan

Resume

COVID-19 poses a real threat to patients with comorbid conditions such as,  diabetes mellitus (DM), hypertension, cardiovascular, renal or hepatic disorders. Kidney damage is very likely in people with diabetes who have undergone a new infection, and the risk of developing acute renal injury is associated with mortality. Potential mechanisms of kidney  involvement in the clinical picture of the disease may include cytokine damage, cross-organ damage, and systemic effects that determine the treatment strategy. These mechanisms are closely interrelated and are important for individuals on extracorporeal therapy and kidney transplants. Autopsy data provide evidence of SARS-CoV-2 virus invasion into kidney tissue  with damage to tubular epithelium cells and podocytes, and red blood cell aggregation in severely COVID-19 patients. By including individuals with chronic kidney disease in planned COVID-19 research protocols, an evidence base for effective and safe treatments can be generated.

Keywords: COVID-19;      hypertension, diabetes mellitus;      acute kidney injury;      dialysis;      kidney transplant

First page

227

Last page

231

For citation: Giyosova Nigora Odiljonovna BASIC MOMENTS OF KIDNEY DAMAGE IN COVID-19 IN PATIENTS WITH COMORBID DISEASES //New Day in Medicine 6(38)2021 227-231 https://cutt.ly/8Y58aON

LIST OF REFERENCES:

  1. Leung C. Clinical features of deaths in the novel Coronavirus epidemic in China. Rev Med Virol. 2020;     30(3):e2103. doi: https://doi.org/10.1002/rmv.2103
  2. Cheng Y, Luo R, Wang K, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020;     97(5):829−838. doi: https://doi.org/10.1016/j.kint.2020.03.005
  3. Tang N, Bai H, Chen X, et al. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020; 18(5):1094−1099. doi: https://doi.org/10.1111/jth.14817
  4. Schoen K, Horvat N, Guerreiro NF, et al. Spectrum of clinical and radiographic findings in patients with diagnosis of H1N1 and correlation with clinical severity. BMC Infect Dis. 2019; 19(1):964. doi: https://doi.org/10.1186/s12879-019-4592-0
  5. Yang JK, Feng Y, Yuan MY, et al. Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabetic Med. 2006; 23(6):623−628. doi: https://doi.org/10.1111/j.1464-5491.2006.01861.x
  6. Banik GR, Alqahtani AS, Booy R, Rashid H. Risk factors for severity and mortality in patients with MERS-CoV: analysis of publicly available data from Saudi Arabia. Virol Sin. 2016; 31(1):81–84. doi: https://doi.org/10.1007/s12250-015-3679-z
  7. Koye DN, Magliano DJ, Nelson RG, Pavkov ME. The global epidemiology of diabetes and kidney disease. Adv Chronic Kidney Dis. 2018;     25(2):121−132. doi: https://doi.org/10.1053/j.ackd.2017.10.011
  8. Fox CS, Matsushita K, Woodward M, et al. Associations of kidney diseases measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet. 2012;     380(98540):1662−1673. doi: https://doi.org/10.1016/S0140-6736(12)61350-6
  9. Larsen CP, Bourne TD, Wilson JD, et al. Collapsing glomerulopathy in a patient with coronavirus disease 2019 (COVID-19). Kidney Int Rep. 2020;     5(6):935−939. doi: https://doi.org/10.1016/j.ekir.2020.04.002
  10. Abdullaeva U.K. Predicting the risk of atrophic transformation in chronic gastritis using serum pepsinogen // World journal of pharmaceutical research, Faculty of Pharmacy Medical University, Bulgaria, Vol. 8, Iss. 13, 2019, P. 219-228.
  11. Abdullaeva U.K., Sobirova G.N., Karimov M.M., Aslonova I.J. The prevalence and possibilities of prevention of noncardial gastric cancer in the Bukhara region // American journal of medicine and medical sciences, 2020, 10(9), Р. 679-681.
  12. Abdullaeva U.K., Shadjanova N.S. Using the OLGA system in chronic atrophic gastritis // New day in medicine, 2020, №2, P. 9-12.
  13. Abdullaeva U.K. The value of interactive teaching methods in improving the level of clinical knowledge of students // Medical education and professional development. 2019, №1 (33), P. 29-32. [in Russian]
  14. Abdullaeva U.K., Jalolova V.Z. Study of the effectiveness of cholelitholytic therapy in patients with cholelithiasis, tARDng into account the type of violation of the contractility of the gallbladder // Bulletin of the Council of Young Scientists and Specialists of the Chelyabinsk Region. 2016. Vol. 5, Issue 4(15), P. 85-86 [in Russian]
  15. Abdullaeva U.K., Mirzaeva D.B. Regional prospects for metabolic therapy for stable senocardia Summary. // Bulletin of the South Kazakhstan Medical Academyю 2019. P. 74-76 [in Russian]
  16. Abdullaeva U.K. Predicting the risk of atrophic transformation in gastritis associated with chronic Helicobacter pylori // abstract of PhD dissertation on medical sciences. Tashkent. 2021. 46-p.
  17. The team of Zhong Nanshan responded that the isolation of SARS-CoV-2 from urine remind us to pay more attention to the cleaning of individuals and families. Guangzhou Daily [cited 2020 February 22].
  18. Chu KH, Tsang WK, Tang CS, et al, Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Kidney Int. 2005;     67(2):698–705. doi: https://doi.org/10.1111/j.1523-1755.2005.67130.x
  19. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;     395(10223):507–513. doi: https://doi.org/10.1016/S0140-6736(20)30211-7
  20. Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. https://doi.org/10.1056/NEJMoa2002032 14. Li Z, Wu M, Guo J, et al. Caution on kidney dysfunctions of 2019-nCoV patients. medRxiv. 2020. https://doi.org/10.1101/2020.02.08.20021212

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