14 -4 (78) 2025 - Khamdamova M.T., Umidova N.N. - GENETIC FACTORS OF GENITAL ENDOMETRIOSIS

GENETIC FACTORS OF GENITAL ENDOMETRIOSIS

Khamdamova M.T. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Umidova N.N. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Frequency of occurrence of individual polymorphic genes of estrogen metabolism enzymes CYP1A1 A-4889G (allele G and genotypes GG, AG) and CYP1A2 C-734A (allele A and genotypes CA, AA), cytokine genes IL1B C511T (allele T), IL2 T-330G (allele G), IL4 C-590T (allele T), IL6 G-174C (allele C and genotype CC), IL10 C-592A (allele A and genotypes CA, AA), TNFА G-308A (allele A and genotype AA), TGFB C-509T (allele T and genotype CT) and genes of angiogenesis factors VEGF G-405C (allele C and genotype GC) and G-1154A (allele A and genotypes GA, AA), KDR T-604C (allele C and genotypes TC, CC), Ang2 G-735A (allele A and genotypes GA, AA) in women with external genital endometriosis are higher than in women without endometriosis.

Keywords: polymorphic genes, endometriosis, allele C, allele T, allele G.

First page

82

Last page

87

For citation:Khamdamova M.T., Umidova N.N. - GENETIC FACTORS OF GENITAL ENDOMETRIOSIS//New Day in Medicine 4(78)2025 82-87 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

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