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  • 18 -4 (77) 2025 - Yusupov Sh.A., Khakimova L.R. - A PERSONALISED APPROACH TO THE MANAGEMENT OF CHILDREN WITH UROLITHIASIS IN A PRIMARY HEALTH CARE

18 -4 (77) 2025 - Yusupov Sh.A., Khakimova L.R. - A PERSONALISED APPROACH TO THE MANAGEMENT OF CHILDREN WITH UROLITHIASIS IN A PRIMARY HEALTH CARE

A PERSONALISED APPROACH TO THE MANAGEMENT OF CHILDREN WITH UROLITHIASIS IN A PRIMARY HEALTH CARE

Yusupov Sh.A. - Samarkand State Medical University Uzbekistan

Khakimova L.R. - Samarkand State Medical University Uzbekistan

Sataev V.U. - Kazan State Medical Academy, Kazan, Republic of Tatarstan, Russia

Rabbimova Z. Sh. - Samarkand Specialised Children's Surgical Clinic of Samarkand State Medical University

Razin M.P. - Kirov State Medical University, Kirov, Russia

Mamatov J. - Samarkand State Medical University Uzbekistan

Murodov U. - Samarkand State Medical University Uzbekistan

Chulyukina A. - Samarkand State Medical University Uzbekistan

Resume

Today urolithiasis is not only a medical problem, but also a serious socio-economic and demographic problem. Therefore, it is very important to timely identify risk factors for the spread of urolithiasis in the population and implement measures aimed at preventing complications, as well as the subsequent increase in the range of medical and social care, reducing disability and improving the quality of life. Objective. To develop a scientifically based algorithm for prediction and early diagnosis of urolithiasis in children in primary health care. Material and methods. The study included children (n=100) with urolithiasis - the main group, relatively healthy children (n=100) - the control group; and their parents. Using the developed questionnaire, an in-depth analysis was carried out to assess the life history of children and their parents, taking into account the course of pregnancy in the mother, the presence of chronic diseases of the parents, as well as the status of stone-forming substances, that is biochemical studies of blood and urine. Results. The developed algorithm for early diagnosis and prognosis of urolithiasis in children in a polyclinic will allow to identify the risk group with the construction of a personalised approach to patient routing at the stages of observation. Children scoring from 4 to 6 points and included in the average risk group also require clinical, laboratory and instrumental investigations. Patients found to have clinical and/or laboratory and instrumental changes in urolithiasis should be referred to a paediatric urologist in a specialised clinic for further comprehensive examination and treatment. If the results of clinical, laboratory and instrumental methods of investigation do not reveal signs of urolithiasis, immunogenetic analysis is recommended. The analysis of the conducted studies has shown that patients with high risk of urolithiasis development (from 7 to 10 points), require special attention. If clinical signs of the disease are detected in children, they are referred to a paediatric urologist of a specialised clinic. In the absence of clinical signs of urolithiasis, laboratory and instrumental investigations should be performed. Children with relevant changes in laboratory tests and ultrasonography of the urinary tract should be referred to a paediatric urologist in a specialised clinic. In the absence of changes in laboratory tests and ultrasound data, immunogenetic testing is performed. Children with a high risk of developing urolithiasis and in the presence of gene polymorphism there is a need for a set of measures to prevent the development of urinary stone disease. In cases where changes at the gene level are not detected, children should be under the supervision of a doctor in an outpatient clinic. Conclusion. The developed algorithm of early diagnosis and prediction of urolithiasis development in children in the conditions of primary care will allow to identify the risk group with the construction of a personalised approach to the patient's routing at the stages of observation.

Key words: urolithiasis in children, prediction, early diagnosis, genetic factor, prelithiasis, diagnostic algorithm.

First page

99

Last page

106

For citation:Yusupov Sh.A., Khakimova L.R., Sataev V.U., Rabbimova Z. Sh., Razin M.P., Mamatov J., Murodov U., Chulyukina A. - A PERSONALISED APPROACH TO THE MANAGEMENT OF CHILDREN WITH UROLITHIASIS IN A PRIMARY HEALTH CARE//New Day in Medicine 4(78)2025 99-106 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

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