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  • 92 -4 (78) 2025 - Khayriyeva D.U. - MORPHOLOGICAL AND MORPHOFUNCTIONAL CHANGES IN THE PANCREAS IN VARIOUS DEGREES OF ACETIC ACID BURNS OF THE DIGESTIVE TRACT: A LITERATURE REVIEW

92 -4 (78) 2025 - Khayriyeva D.U. - MORPHOLOGICAL AND MORPHOFUNCTIONAL CHANGES IN THE PANCREAS IN VARIOUS DEGREES OF ACETIC ACID BURNS OF THE DIGESTIVE TRACT: A LITERATURE REVIEW

MORPHOLOGICAL AND MORPHOFUNCTIONAL CHANGES IN THE PANCREAS IN VARIOUS DEGREES OF ACETIC ACID BURNS OF THE DIGESTIVE TRACT: A LITERATURE REVIEW

Khayriyeva D.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Acetic acid ingestion leads to severe corrosive burns in the digestive tract, affecting not only the esophagus and stomach but also distant organs such as the pancreas. The pancreas, being crucial for both endocrine and exocrine functions, undergoes significant morphological and functional changes due to acetic acid exposure. This literature review summarizes recent research on the histopathological, vascular, and functional alterations in the pancreas following acetic acid-induced burns. The mechanisms underlying these changes, including oxidative stress, systemic inflammatory response, and neurohormonal dysregulation, are analyzed. The review also explores the clinical implications of pancreatic dysfunction, such as digestive insufficiency, endocrine disorders, and long-term complications like fibrosis and pancreatitis. Understanding these effects is crucial for improving early diagnosis and treatment strategies. Further studies are required to develop targeted therapeutic interventions to mitigate pancreatic damage in cases of corrosive ingestion.

Keywords. Acetic acid burns, corrosive injury, pancreas, pancreatic morphology, exocrine dysfunction, endocrine dysfunction, oxidative stress, systemic inflammatory response, digestive tract injury, pancreatic fibrosis.

First page

542

Last page

547

For citation:Khayriyeva D.U. - MORPHOLOGICAL AND MORPHOFUNCTIONAL CHANGES IN THE PANCREAS IN VARIOUS DEGREES OF ACETIC ACID BURNS OF THE DIGESTIVE TRACT: A LITERATURE REVIEW//New Day in Medicine 4(78)2025 542-547 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

List of References

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