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  • 126 -4 (78) 2025 - Akhmedov F.K., Akhmadjonova G.M. - MORPHOLOGICAL ASPECTS OF PATHOGENESIS, NEW METHODS OF DIAGNOSTICS AND TREATMENT OF PREECLAMPSIA

126 -4 (78) 2025 - Akhmedov F.K., Akhmadjonova G.M. - MORPHOLOGICAL ASPECTS OF PATHOGENESIS, NEW METHODS OF DIAGNOSTICS AND TREATMENT OF PREECLAMPSIA

MORPHOLOGICAL ASPECTS OF PATHOGENESIS, NEW METHODS OF DIAGNOSTICS AND TREATMENT OF PREECLAMPSIA

Akhmedov F.K. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Akhmadjonova G.M. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Negmatshaeva M.S. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Negmatshaeva H.N. - Bukhara State Medical Institute named after Abu Ali ibn Sina, Andijan State Medical Institute

Resume

Preeclampsia is a complication of pregnancy that is associated with significant maternal and fetal morbidity and mortality. The disease manifests itself as newly diagnosed hypertension and often proteinuria in the mother, which can progress to multiple organ dysfunction, including liver, kidney and cerebral disease if the fetus and placenta are not born. Maternal endothelial dysfunction due to circulating factors of fetal origin from the placenta is a hallmark of preeclampsia. In this review, the authors provide information on the latest research conducted in the study of the etiopathogenesis of preeclampsia and new diagnostic methods.

Key words: preeclampsia, eclampsia, maternal and perinatal mortality, obstetric pathology.

First page

722

Last page

728

For citation:Akhmedov F.K., Akhmadjonova G.M., Negmatshaeva M.S., Negmatshaeva H.N. - MORPHOLOGICAL ASPECTS OF PATHOGENESIS, NEW METHODS OF DIAGNOSTICS AND TREATMENT OF PREECLAMPSIA//New Day in Medicine 4(78)2025 722-728 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

List of References

  1. COG Committee Opinion No. 651 Summary: Menstruation in Girls and Adolescents: Using the Menstrual Cycle as a Vital Sign. Obstet Gynecol. 2015; 126 (6): 1328.
  2. Agents stimulating gonadal function in the human. Report of a WHO scientific group. World Health Organ Tech Rep Ser. 1976; 514.
  3. American Academy of Pediatrics Committee on Adolescence, American College of Obstetricians and Gynecologists Committee on Adolescent Health Care Diaz A, Laufer MR, Breech LL. Menstruation in girls and adolescents: using the menstrual cycle as a vital sign. Pediatrics 2006; 118(5): 2245–50.
  4. ASRM - Practice Committee of the American Society for Reproductive Medicine. Fertility evaluation of infertile women: a committee opinion. Fertil Steril 2021; 116(5): 1255–65.
  5. ASRM - SREI Practice Committee of the American Society for Reproductive Medicine in collaboration with the Practice Committee of the Society for Reproductive Endocrinology and Infertility. Optimizing natural fertility: a committee opinion. Fertil Steril. 2013; 100(3): 631-637.
  6. Balen A. The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology. Best Pract Res Clin Obstet Gynaecol. 2004; 18(5): 685-706.
  7. Balen A.H., Morley L.C., Misso M., et al. The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance. Hum Reprod Update. 2016; 22(6): 687-708.
  8. Bashir S.T., Baerwald A.R., Gastal M.O., Pierson R.A., Gastal E.L. Follicle growth and endocrine dynamics in women with spontaneous luteinized unruptured follicles versus ovulation. Hum Reprod. 2018; 33(6): 1130-1140.
  9. Bellamy L., Casas J.P., Hingorani AD & Williams DJ Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 335, 974 (2007).
  10. Dewailly D, Lujan ME, Carmina E, et al. Definition and significance of polycystic ovarian morphology: a task force report from the Androgen Excess and Polycystic Ovary Syndrome Society. Hum Reprod Update. 2014; 20(3): 334-352.
  11. ESHRE Capri Workshop Group. Health and fertility in World Health Organization group 2 anovulatory women. Hum Reprod Update. 2012; 18(5): 586-599.
  12. ESHRE/ASRM Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004; 19(1): 41-47.
  13. Fauser BC, Tarlatzis BC, Rebar RW, et al. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertil Steril. 2012; 97(1): 28-38 e25.
  14. Fraser I.S., Critchley H.O., Munro M.G., Broder M. A process designed to lead to international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding. Fertil Steril. 2007; 87(3): 466-476.
  15. Fraser I.S., Critchley H.O., Munro M.G., Broder M. Can we achieve international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding? Hum Reprod. 2007; 22(3): 635-643.
  16. Fraser I.S., Critchley H.O., Munro M.G., Broder M. Writing Group for this Menstrual Agreement P. A process designed to lead to international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding. Fertil Steril. 2007; 87(3): 466-476.
  17. Frisch R.E. Body fat, menarche, fitness and fertility. Hum Reprod. 1987; 2(6): 521-533.
  18. Giviziez CR, Sanchez EGM, Lima YAR, Approbato MS. Association of Overweight and Consistent Anovulation among Infertile Women with Regular Menstrual Cycle: A Case-control Study. Rev Bras Ginecol Obstet. 2021; 43(11): 834-839.
  19. Hale G.E., Hughes C.L., Burger H.G., Robertson D.M., Fraser I.S. Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition. Menopause. 2009; 16(1): 50-59.
  20. Hickey M., Balen A. Menstrual disorders in adolescence: investigation and management. Hum Reprod Update. 2003; 9(5): 493-504.

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