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  • 127 -4 (78) 2025 - Shodieva M.S. - EVALUATION OF THE PARAMETERS OF THE IMMUNE SYSTEM IN CHILDREN WITH GASTRODUODENAL PATHOLOGY

127 -4 (78) 2025 - Shodieva M.S. - EVALUATION OF THE PARAMETERS OF THE IMMUNE SYSTEM IN CHILDREN WITH GASTRODUODENAL PATHOLOGY

EVALUATION OF THE PARAMETERS OF THE IMMUNE SYSTEM IN CHILDREN WITH GASTRODUODENAL PATHOLOGY

Shodieva M.S. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

In children, immunity to X pylori infection at an early stage can serve as a kind of model of pathological reaction and learning. In the conditions of the Republic of Uzbekistan, such studies have not been conducted, however, weight gain, a tendency to rejuvenation and a high incidence of complications dictate the need to study this issue. Patients and methods. The purpose of the study out of the entire cohort of examined children, children with gastroduodenal pathology associated and unrelated to CP were included in the study. We studied the mediators of the immune response using the example of IL-1ß and TNF-α in 165 sick children and almost healthy children aged 50 years, who made up a control group for comparison.H. pylori " + " and X. pylori " - " pathologies of the gastroduodenal zone are divided by age into 2 subgroups.Results: IL-1B levels in the control group of children aged 7-14 years were 21.6±0.86 pg/ml compared with 24.2±0.72 pg/ml in children aged 15-18 years. In children aged 15-18 years, 27.4± 0.76 pg/ml.

Key words: children, gastroduodenitis, peptic ulcer, Helicobacter pylori, immunology, genetics.

First page

729

Last page

731

For citation:Shodieva M.S. - EVALUATION OF THE PARAMETERS OF THE IMMUNE SYSTEM IN CHILDREN WITH GASTRODUODENAL PATHOLOGY//New Day in Medicine 4(78)2025 729-731 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

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