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  • 151 -4 (78) 2025 - Khamdamov B.Z., Nabieva U.P. - LOCAL AND SYSTEMIC IMMUNOINFLAMMATORY STATUS OF ARTHROTIC ARTHRITIS PATIENTS

151 -4 (78) 2025 - Khamdamov B.Z., Nabieva U.P. - LOCAL AND SYSTEMIC IMMUNOINFLAMMATORY STATUS OF ARTHROTIC ARTHRITIS PATIENTS

LOCAL AND SYSTEMIC IMMUNOINFLAMMATORY STATUS OF ARTHROTIC ARTHRITIS PATIENTS

Khamdamov B.Z. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Nabieva U.P. - Institute of Human Immunology and Genomics of the Academy of Sciences of the Republic of Uzbekistan

Rasulov G.M. - National Center for Rehabilitation of Disabled People and Prosthetics

Resume

The obtained data allow us to talk about the clinical and pathogenetic features of AA progression in various age groups. In middle-aged patients, the most significant increase in the concentration of IL-6 and CRP in the synovial fluid was noted, which indicates the decisive value of local inflammation in this age group. In addition, patients with AA of this age group showed the most significant decrease in adaptive reserves with a pronounced imbalance in the content of IL-6 and its soluble receptor.

Keywords: arthrotic arthritis, synovial fluid, immunoinflammation, CRP, interleukin 6, interleukin 8

First page

850

Last page

855

For citation:Khamdamov B.Z., Nabieva U.P., Rasulov G.M. - LOCAL AND SYSTEMIC IMMUNOINFLAMMATORY STATUS OF ARTHROTIC ARTHRITIS PATIENTS//New Day in Medicine 4(78)2025 850-855 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

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