184 -4 (78) 2025 - Boltaev M.M. - INFLUENCE OF PHYTOCHEMICAL COMPONENTS OF BROCCOLI ON GASTRITIS AND GASTRIC ULCER DISEASE

INFLUENCE OF PHYTOCHEMICAL COMPONENTS OF BROCCOLI ON GASTRITIS AND GASTRIC ULCER DISEASE

Boltaev M.M. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Cruciferous vegetables are rich sources of many phytochemicals, including indole derivatives, dithiolthiones, and isothiocyanates. 3-Indolylmethylglucosinolate is a natural hydrolysis product of glucobrassicin, which is found in cruciferous vegetables such as broccoli, Brussels sprouts, and cauliflower. Phytochemical components of broccoli such as indole-3-carbinol, 3,3-diindolylmethane, and sulforaphane can significantly protect gastric tissue from gastritis and gastric ulcer induced by ASA and high numbers of proliferating cells (COX-2 and PCNA) in the stomach. Epidemiological studies suggest that high intake of cruciferous vegetables is associated with a lower risk of cancer, and it is possible that the chemopreventive properties are partly due to 3-indolylmethylglucosinolate

Key words: Broccoli, indole-3-carbinol, gastritis and gastric ulcer

First page

1032

Last page

1034

For citation:Boltaev M.M. - INFLUENCE OF PHYTOCHEMICAL COMPONENTS OF BROCCOLI ON GASTRITIS AND GASTRIC ULCER DISEASE//New Day in Medicine 4(78)2025 1032-1034 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

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