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  • 212 -4 (78) 2025 - Makhramov U.T., Otamurod B.M. - IMPROVING PERSONALIZED DIAGNOSIS AND THERAPY OF BRONCHIAL ASTHMA BASED ON THE ASSESSMENT OF ADIPOKINES AND IMMUNOLOGICAL BIOMARKERS

212 -4 (78) 2025 - Makhramov U.T., Otamurod B.M. - IMPROVING PERSONALIZED DIAGNOSIS AND THERAPY OF BRONCHIAL ASTHMA BASED ON THE ASSESSMENT OF ADIPOKINES AND IMMUNOLOGICAL BIOMARKERS

IMPROVING PERSONALIZED DIAGNOSIS AND THERAPY OF BRONCHIAL ASTHMA BASED ON THE ASSESSMENT OF ADIPOKINES AND IMMUNOLOGICAL BIOMARKERS

Makhramov U.T. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Otamurod B.M. - Samarkand State Medical University

Resume

This article explores modern aspects of the pathogenesis, diagnosis, and treatment of bronchial asthma (BA), with a focus on the assessment of adipokines (leptin, adiponectin) and immunological biomarkers (IgE, IL-4, IL-5, IL-13). The review includes data from scientific literature, clinical studies, as well as recommendations from GINA and national protocols. An analysis of BA phenotypes is provided, principles of stepwise therapy are discussed, along with emerging classes of drugs (anti-IgE, anti-IL-5). The significance of metabolic and immune dysregulation in the development of severe forms of BA is emphasized

Keywords: bronchial asthma, adipokines, leptin, adiponectin, immunological biomarkers, cytokines, IgE, IL-5, personalized medicine, therapy

First page

1166

Last page

1169

For citation:Makhramov U.T., Otamurod B.M. - IMPROVING PERSONALIZED DIAGNOSIS AND THERAPY OF BRONCHIAL ASTHMA BASED ON THE ASSESSMENT OF ADIPOKINES AND IMMUNOLOGICAL BIOMARKERS//New Day in Medicine 4(78)2025 1166-1169 https://newdayworldmedicine.com/en/new_day_medicine/4-78-2025

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