22 -5 (79) 2025 - Rozixodjaeva G.A., Usmanova Z.A. - SERUM LEVELS OF MATRIX METALLOPROTEINASES-9 (MMP-9) AND THEIR INHIBITORS (TIMP-1) AS BIOMARKERS OF CAROTID ATHEROSCLEROTIC PLAQUE IN

SERUM LEVELS OF MATRIX METALLOPROTEINASES-9 (MMP-9) AND THEIR INHIBITORS (TIMP-1) AS BIOMARKERS OF CAROTID ATHEROSCLEROTIC PLAQUE INSTABILITY

Rozixodjaeva G.A. - Central Clinical Hospital No. 1 of the Main Medical Department under the Administration of the President of the Republic of Uzbekistan

Usmanova Z.A. - Center for the Development of Professional Qualifications of Medical Workers

Sha-Akhmedova L.R. - Center for the Development of Professional Qualifications of Medical Workers

Akhmatkhodjaeva D.A. - Center for the Development of Professional Qualifications of Medical Workers

Plugar V.I. - Center for the Development of Professional Qualifications of Medical Workers

Fayziyev B.S. - Center for the Development of Professional Qualifications of Medical Workers

Resume

This study investigated the levels of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in the blood serum of patients with carotid atherosclerosis. In patients with unstable atherosclerotic plaques in the carotid artery (according to histological analysis), an imbalance between MMP-9 and TIMP-1 was observed. Elevated serum levels of MMP-9, TIMP-1, and their ratio were detected in these patients.

Key words: matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, stable and unstable atherosclerotic plaques, carotid atherosclerosis.

First page

106

Last page

110

For citation:Rozixodjaeva G.A., Usmanova Z.A., Sha-Akhmedova L.R., Akhmatkhodjaeva D.A., Plugar V.I., Fayziyev B.S. - SERUM LEVELS OF MATRIX METALLOPROTEINASES-9 (MMP-9) AND THEIR INHIBITORS (TIMP-1) AS BIOMARKERS OF CAROTID ATHEROSCLEROTIC PLAQUE INSTABILITY//New Day in Medicine 5(79)2025 106-110 https://newdayworldmedicine.com/en/new_day_medicine/5-79-2025

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