127 -5 (79) 2025 - Oblokulov A.R. - VALUES OF HUMORAL IMMUNITY INDICES IN DISEASE PROGNOSIS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS B WITH DELTA AGENT

VALUES OF HUMORAL IMMUNITY INDICES IN DISEASE PROGNOSIS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS B WITH DELTA AGENT

Oblokulov A.R. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

In order to study the characterization of humoral immunity parameters in patients with cirrhosis developed due to chronic viral hepatitis B with delta agent, 105 patients with chronic viral hepatitis D with advanced cirrhosis and 62 patients with advanced cirrhosis were examined. It was recommended as a diagnostic and prognostic immunologic criterion for IgG level determination

Key words: chronic viral hepatitis D, liver cirrhosis, Delta agent, IgA, IgM, IgG, prognosis

First page

623

Last page

626

For citation:Oblokulov A.R. - VALUES OF HUMORAL IMMUNITY INDICES IN DISEASE PROGNOSIS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS B WITH DELTA AGENT//New Day in Medicine 5(79)2025 623-626 https://newdayworldmedicine.com/en/new_day_medicine/5-79-2025

List of References

1. Исаева О.В., Кюрегян К.К., Магомедова С.А., Михайлов М.И. Вирусный гепатит дельта: возможности терапии. Терапия. 2023, 9(3), 69–77.
2. Negro F, Lok A. Hepatitis D: a review. JAMA. 2023 26;330(24):2376-2387.
3. Asselah T, Rizzetto M. Hepatitis D virus infection. N Engl J Med. 2023 Jul 6;389(1):58-70.
4. European Association for the Study of the Liver. EASL Clinical Practice Guidelines on hepatitis delta virus. J Hepatol. 2023 Aug;79(2):433-460.,
5. Buti M, Gonzalez A, Riveiro-Barciela M, Bourliere M. Management of chronic HBV-HDV patients chronic HBV-HDV infection: A review on new management options. United European Gastroenterol J. 2024 Mar;12(2):210-218.
6. Chen H, Shen D, Ji D, et al. Prevalence and burden of hepatitis D virus infection in the global population: a systematic review and meta-analysis. Gut. 2019 Mar;68(3):512-521.
7. Miao Z, Zhang S, Ou X, et al. Estimating the global prevalence, disease progression, and clinical outcome of hepatitis delta virus infection. J Infect Dis. 2020 Apr 27;221(10):1677-1687.
8. Stockdale A, Kreuels B, Henrion M, et al. The global prevalence of hepatitis D virus infection: systematic review and meta-analysis. J Hepatol. 2020, 73, 523–532.
9. Абдурахманов Д.Т., Есмембетов К.И., Никулкина Е.Н. с соавт. Хронический гепатит дельта: современное состояние проблемы и перспективы лечения. Клиническая фармакология и терапия. 2019, 28: 26-34.
10. Gish R, Wong R, Di Tanna G, et al. Association of hepatitis delta virus with liver morbidity and mortality: A systematic literature review and meta-analysis. Hepatology. 2024 May 1;79(5):1129-1140.

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