140 -5 (79) 2025 - Mamasaliev N.S., Sadikkhodjaev S.Sh. - FEATURES OF THE DEVELOPMENT AND PROGRESSION OF TUBERCULOSIS LESIONS OF THE LUNG AGAINST THE BACKGROUND OF COVID-19 INFECTION
FEATURES OF THE DEVELOPMENT AND PROGRESSION OF TUBERCULOSIS LESIONS OF THE LUNG AGAINST THE BACKGROUND OF COVID-19 INFECTION
Mamasaliev N.S. - Andijan State Medical Institute
Sadikkhodjaev S.Sh. - Andijan State Medical Institute
Khakimova R.A. - Andijan State Medical Institute
Mamasaliev Z.N. - Andijan State Medical Institute
Kurbonova R.R. - Andijan State Medical Institute
Resume
According to the World Health Organization (WHO) for 2019, 10 million people in the world are infected with tuberculosis, including 5.6 million men, 3.2 million women and 1.2 million children. It is estimated that 1 million children worldwide suffer from tuberculosis every year. The reduction in the incidence rate from 2015 to 2019 was 9%, and the global goal for 2030 was 80%. Therefore, the main task of anti-tuberculosis and practical work is to prevent the development of tuberculosis lung lesions, including in comorbidity and especially against the background of the pandemic growth of COVID-19 among the population. Only on the basis of screening and "targeted" formation of groups of low, medium, high and very high risk of COVID-19 patients for tuberculosis lung lesions and modern implementation of primary, secondary or tertiary prevention measures can solve this currently extremely urgent task. In this article, it was concluded that in the absence of clinical manifestations of an active form of tuberculosis infection, there is a constant state of immunoassay caused by the presence of mycobacterium tuberculosis antigens in the body, there is no "gold standard" diagnosis that allows a direct method to identify an infection in which mycobacterium tuberculosis occurs in humans, most infected individuals do not have It is believed that Lti is 10% probability of transition to active tuberculosis, 5% in the first two years of infection and 5% for the rest of a person's life. In addition, the article emphasizes that the placement of persons who, as is known from mathematical models, about 30% of the world's population are considered carriers of lti, who are at risk of developing active tuberculosis for the detection and preventive treatment of persons with lt, is very important for the elimination of the disease.
Keywords: COVID - 19, tuberculosis lung lesions, clinical and epidemiological characteristics.
First page
696
Last page
701
For citation:Mamasaliev N.S., Sadikkhodjaev S.Sh., Khakimova R.A., Mamasaliev Z.N., Kurbonova R.R. - FEATURES OF THE DEVELOPMENT AND PROGRESSION OF TUBERCULOSIS LESIONS OF THE LUNG AGAINST THE BACKGROUND OF COVID-19 INFECTION//New Day in Medicine 5(79)2025 696-701 https://newdayworldmedicine.com/en/new_day_medicine/5-79-2025
List of References
- Временные методические рекомендации М3 РФ «Профилактика, диагностика и лечение новой коронавирусной инфекции (Covid - 19). Версия 9». (утв. Министерством здравоохранения РФ 26 октября 2020 г).
- Временные методические рекомендации по оказанию противотуберкулезной помощи в условиях пандемии новой короновирусной инфекции (Covid - 19) (уев. президиумом Российского общества фтизиатров и президиумом Ассоциации фтизиатров 28.04.2020г).
- Головкин A.C., Кудрявцев И.В., Дмитриев A.B., Калинина О.В.
- Фиброзные изменения сердечно - сосудистой и дыхательной систем после перенесенной Covid -19: вклад факторов иммунной системы и генетическая предраспположенность: // Российский кардиологический журнал. - 2020. - Т. 25. № 10. - С. 215 - 219. - DOI: 10.15829/1560 - 4071- 2020 - 4087.
- Екатеринчева О.Л., Малкова А.М., Карев В.Е., Кудрявцев И.В., Зинченко Ю.С., Потепун Т.Б., Кудлай Д.А., Старшинова А.А. Особенности диагностики туберкулеза на фоне Covid - 19 // Журнал инфектологии. - 2021. -Т. 13.№ 1.-С. 117-123.
- Кравченко А. Ф., Прокопьев Е. С., Яковлева Л. П., Лукина А. М., Лугинова Е. Ф., Валь Н. С. Внедрение новых технологий по амбулаторно поликлинической помощи больным туберкулезом в условиях пандемии COVID-19 в Республике Саха (Якутия)//Туберкулёз и болезни лёгких. - 2020. - Т. 98, No 12. - С. 20-24. http://doi.org/!0.21.292/2075-1230-2020-98-12- 20-24.
- Нечаева О.Б. Состояние и перспективы противотуберкулезной службы России в период Covid - 19// Туб. и болезни легких. - 2020. - Т. 98. № 12-С. 7- 19. https://doi.org/10.21292/2075 - 1230-2020-98- 12-7- 19.
- Никулина Е. Л. Аллельный полиморфизм гена при туберкулезе легких //Медицинская иммунология. - 2010. - Т. 12, № 3. - С. 260-263.
- Стерликов С.А., Сои И.М., Саенко С.С. Русакова Л.И., Галкии В.Б. Возможное влияние пандемии Covid - 19 на эпидемическую ситуацию по туберкулезу // Современные проблемы здравоохранения и медицинской статистики. - 2020. - № 2. - С. 191 - 205. doi: 10.24411/2312- 2935 - 2020 - 00042.
- Ackermann M., Verleden S.E., Kuehnel M., et al. Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid - 19. // New England Journal of Medicine. - 2020. - Vol. 383. no 2. - P. 121 - 125.
- Akiyama Y. et al. Non-COVID-19 patients with life-threatening diseases who visiteda fever clinic: a single-center, observational study in Tokyo, Japan // Intern. Med. -2020. - Vol. 59, No 24. - P. 3131-3133. DOI:10.2169/internalmedicine.5614-20.
- Drain P.K., Bajema K.L., Dowdy D., Dhedak. Naidoo K., Schumacher S.G. Ma S., Meermlier E. Lewinsohn D.M., Sherman D. R. Incipient and Subclinal Tuberculosis: Clinical Review of early Stages and Progression of Infection // Clin Microbiol Rev. - 2018. - Vol. 31 № 4. - P. 00021 - 00018. https://doi.org/10.1028/CMR. 00021 - 18.
- Global Tuberculosis Report 2021/Geneva:WHO. 2021.-43 C.-ISBN: 978 -92 - 4 - 003702 - 1.
- Gupta R.K., Lule S.A., Krutikov M., et al. Screening for tuberculosis among high - risk groups attending London emergency departments: a prospective observational study. Eur Respir J. 2021; 57: 2003831. DOI: https://doi. org/10.1183/13993003.03831 -2020.
- Light R., Richard W. Update on tuberculous pleural effusion //' Respirologv.-2010. -У» 15. - P 451-458.
- Ling Lin Lianfeng Lu. Wei Cao. Taisheng Li. Hypothesis for potential pathogenesis of SARS - Cov - 2 infection - a review of immune changes in patients with vival pneumonia Emerg Microbes Infect. 2020:9(1):727 - 732. https://doi.org/10.1080/22221751.2020.1746199.
- Petrikov SS, Kholmogorova AB, Suroegina AY, et al. Professional burnout, symptoms of emotional disorders and distress among healthcare professionals during the Covid - 19 epidemic. Counseling Psychology and Psychotherapy.2020; 28(2): 8 - 45. https://doi.org./10.17759/cpp.2020280202.
- Restored E., Shaker B.S., Naqibullah M., et al. Chest X - ray findings in tuberculosis patients identified by passive and active case finding: a retrospective study. J Clin Tuberc Other Mycobact Dis. 2019: 14: 27 - 29.DOI: https://doi.org/10.1016/j.ictube. 2019.01.003.
- Tadolini M., Codecasa L. R., Garcia-Garcia J. M., Blanc F. X., et al. Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases // Eur. Respir.J.-2020.-Vol.56, No 1. https://doi.org/10.1183/13993003.Q1398- 2020.
file
download