157 -5 (79) 2025 - Jabborova F.U. - IMMUNOPATHOGENETIC ASPECTS OF INFLAMMATORY PERIODONTAL TISSUE DISEASES IN THE ELDERLY AND SENILE

IMMUNOPATHOGENETIC ASPECTS OF INFLAMMATORY PERIODONTAL TISSUE DISEASES IN THE ELDERLY AND SENILE

Jabborova F.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The purpose of this review is to analyze current understanding of the role of age-related changes in the immune system in the development of inflammatory periodontal diseases (IBD) in elderly and senile people. The publications from international and Russian scientific databases for the period 2000-2024 are analyzed, with an emphasis on immune senescence, cytokine imbalance and the phenomenon of inflammaging. It was revealed that aging is accompanied by a violation of both innate and adaptive immunity, increased production of pro-inflammatory cytokines and destruction of periodontal tissues. Understanding these mechanisms is of key importance for the development of personalized therapeutic approaches in gerontological dentistry

Key words: periodontitis, aging, immunity, cytokines, inflammation aging, elderly

First page

779

Last page

782

For citation:Jabborova F.U. - IMMUNOPATHOGENETIC ASPECTS OF INFLAMMATORY PERIODONTAL TISSUE DISEASES IN THE ELDERLY AND SENILE//New Day in Medicine 5(79)2025 779-782 https://newdayworldmedicine.com/en/new_day_medicine/5-79-2025

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