211 -5 (79) 2025 - Bekmurodova O.K. - ASSESSMENT OF CORNEAL THICKNESS CHANGES IN PATIENTS WITH HIGH MYOPIA: A MORPHOMETRIC STUDY AMONG SCHOOLCHILDREN IN UZBEKISTAN

ASSESSMENT OF CORNEAL THICKNESS CHANGES IN PATIENTS WITH HIGH MYOPIA: A MORPHOMETRIC STUDY AMONG SCHOOLCHILDREN IN UZBEKISTAN

Bekmurodova O.K. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The cornea is the most important part of the eye, providing protection and optimal light transmission. Its thickness can affect refractive errors and is important for various eye diseases. This study examined the thickness of the cornea in young girls with nearsightedness compared with emmetropes. The study aimed to analyze the optical components of the eye in young women with myopia and evaluate morphological characteristics. Materials and methods. It was performed based on the Bukhara Institute of Eye Microsurgery, with the participation of 100 patients with myopia and 120 emmetropes. The central and peripheral thickness of the cornea was assessed using optical coherence tomography (OCT). Statistical analysis was performed using IBM SPSS, including independent t-tests and calculations of the magnitude of the effect. Results. The central thickness of the cornea in short-sighted people was significantly thinner than in emmetropes (short-sighted boys: 534.5 microns, emmetropia: 554.5 microns) - similar significant differences were noted in the upper and lower regions of the cornea. The differences between nearsighted and emmetropes were statistically significant (p <0.05). Cohen's coefficient d values indicated a strong negative correlation between myopia and corneal thickness, especially in boys. Conclusion. This study is groundbreaking for the Uzbek community and demonstrates that myopic girls tend to have thinner corneas than their emmetropic peers. The comparative thickness results show similarities with other populations, with minor differences due to environmental conditions

Key words: central thickness of the cornea, myopia, OCT, peripheral thickness of the cornea

First page

1038

Last page

1043

For citation:Bekmurodova O.K. - ASSESSMENT OF CORNEAL THICKNESS CHANGES IN PATIENTS WITH HIGH MYOPIA: A MORPHOMETRIC STUDY AMONG SCHOOLCHILDREN IN UZBEKISTAN//New Day in Medicine 5(79)2025 1038-1043 https://newdayworldmedicine.com/en/new_day_medicine/5-79-2025

List of References

  1. Chiang, S., Weng, T., Lin, C., & Lin, S. (2019). Ethnic disparity in prevalence and associated risk factors of myopia in adolescents. Journal of the Formosan Medical Association, 119(1), 134–143. https://doi.org/10.1016/j.jfma.2019.03.004
  2. Lee, Y., Shih, Y., Lin, L. L., Huang, J., & Wang, T. (2008). Association between high myopia and progression of visual field loss in primary open-angle glaucoma. Journal of the Formosan Medical Association, 107(12), 952–957. https://doi.org/10.1016/s0929-6646(09)60019-x
  3. Brandt, J. D., Beiser, J. A., Kass, M. A., & Gordon, M. O. (2001). Central corneal thickness in the ocular hypertension treatment study (OHTS). Ophthalmology, 108(10), 1779–1788. https://doi.org/10.1016/s0161-6420(01)00760-6
  4. Tananuvat, N., & Khumchoo, N. (2020). Corneal thickness and endothelial morphology in Normal Thai eyes. BMC Ophthalmology, 20(1). https://doi.org/10.1186/s12886-020-01385-1
  5. Taşlı, N. G., Icel, E., Karakurt, Y., Ucak, T., Ugurlu, A., Yilmaz, H., & Akbas, E. M. (2020). The findings of corneal specular microscopy in patients with type-2 diabetes mellitus. BMC Ophthalmology, 20(1). https://doi.org/10.1186/s12886-020-01488-9
  6. Hosoda, Y., Miyake, M., Meguro, A., Tabara, Y., Iwai, S., Ueda-Arakawa, N., Nakano, E., Mori, Y., Yoshikawa, M., Nakanishi, H., Khor, C., Saw, S., Yamada, R., Matsuda, F., Cheng, C., Mizuki, N., Tsujikawa, A., Yamashiro, K., Tabara, Y., Kosugi, S. (2020). Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study https://doi.org/10.1038/s42003-020-01137-3
  7. Dhallu, S. K., Huarte, S. T., Bilkhu, P. S., Boychev, N., & Wolffsohn, J. S. (2020). Effect of scleral lens oxygen permeability on corneal physiology. Optometry and Vision Science, 97(9), 669–675. https://doi.org/10.1097/opx.0000000000001557
  8. De Castro Olyntho, M. A., Junior, Augusto, L. B., Gracitelli, C. P. B., & Tatham, A. J. (2020). The effect of corneal thickness, densitometry and curvature on intraocular pressure measurements obtained by applanation, rebound and dynamic contour tonometry. Vision, 4(4), 45. https://doi.org/10.3390/vision4040045
  9. Sayah, D. N., Mazzaferri, J., Descovich, D., Costantino, S., & Lesk, M. R. (2020). The association between ocular rigidity and neuroretinal damage in glaucoma. Investigative Ophthalmology & Visual Science, 61(13), 11. https://doi.org/10.1167/iovs.61.13.11
  10. Kim, W. K., Ryu, I. H., Yoo, J., & Kim, S. W. (2020). Effect of gender, age, and Ocular and Growth-Related factors on corneal epithelial and stromal thickness in children. Journal of Clinical Medicine, 9(12), 3849. https://doi.org/10.3390/jcm9123849

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