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  • 73 -6 (80) 2025 - F.A. Ikramova - PATHOPHYSIOLOGICAL ASPECTS OF CARDIOMYOPATHY PROGRESSION IN TYPE 2 DIABETES UNDER HOT CLIMATE EXPOSURE

73 -6 (80) 2025 - F.A. Ikramova - PATHOPHYSIOLOGICAL ASPECTS OF CARDIOMYOPATHY PROGRESSION IN TYPE 2 DIABETES UNDER HOT CLIMATE EXPOSURE

PATHOPHYSIOLOGICAL ASPECTS OF CARDIOMYOPATHY PROGRESSION IN TYPE 2 DIABETES UNDER HOT CLIMATE EXPOSURE

F.A. Ikramova - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

Abstract The purpose of the research: This study aims to assess the clinical and functional characteristics of diabetic cardiomyopathy (DCM) in patients with type 2 diabetes mellitus (T2DM) who reside in regions with hot climates and to identify strategies for optimizing metabolic therapy under these conditions. Research methods: A cohort of 180 patients with T2DM was observed in a regional cardiology center. Clinical, echocardiographic, electrocardiographic, and laboratory evaluations were performed. Patients were divided into two groups depending on the presence or absence of DCM. Statistical analysis was conducted using SPSS v25.0. Research results: Patients with DCM showed significantly more complaints of dyspnea (74%), fatigue (68%), and edema (61%). Diastolic dysfunction (E/A < 1.0) was identified in 71% of DCM patients, while GLS < -17% was observed in 64%. HRV was reduced (SDNN 91 ± 11 ms), and arrhythmias occurred in 38% of cases. HbA1c and NT-proBNP levels were elevated. Electrolyte imbalances were observed in 62% of DCM patients. Practical application: The results support the necessity of climate-adapted therapy for T2DM patients, including adjusted hydration strategies, greater use of cardioprotective antidiabetics, and enhanced patient education on heat stress prevention.

Keywords: Type 2 diabetes mellitus, diabetic cardiomyopathy, hot climate, echocardiography, arrhythmia, metabolic therapy, cardiac function

First page

362

Last page

365

For citation:F.A. Ikramova - PATHOPHYSIOLOGICAL ASPECTS OF CARDIOMYOPATHY PROGRESSION IN TYPE 2 DIABETES UNDER HOT CLIMATE EXPOSURE//New Day in Medicine 6(80)2025 362-365 https://newdayworldmedicine.com/en/new_day_medicine/6-80-2025

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