117 -6 (80) 2025 - Khalimova Z.Y., Sabirov U.Y., Mirsaidova U.A. - ENDOCRINE DYSFUNCTIONS AND DERMATOLOGIC SIGNS: EPIDEMIOLOGY AND DIFFERENTIAL DIAGNOSIS

ENDOCRINE DYSFUNCTIONS AND DERMATOLOGIC SIGNS: EPIDEMIOLOGY AND DIFFERENTIAL DIAGNOSIS

Khalimova Z.Y. - Republican Specialized Scientific and Practical Medical Center of Endocrinology named after Academician Y. Kh. Turakulov, Specialized Hospital

Sabirov U.Y. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan

Mirsaidova U.A. - Republican Specialized Scientific and Practical Center for Dermatovenereology and Cosmetology Uzbekistan

Resume

Background. The skin serves as a visible window to systemic endocrine disorders, with dermatologic manifestations often preceding laboratory abnormalities. This review explores the prevalence and clinical significance of cutaneous signs in endocrine diseases. Materials and Methods. A systematic literature review was conducted using PubMed, Web of Science, and local databases (2010–2024) to analyze epidemiological data and diagnostic pathways. Results. Key findings include: (1) 30–50% of polycystic ovary syndrome (PCOS) patients present with hirsutism/acne, (2) acanthosis nigricans is a marker of insulin resistance in 60–80% of cases, (3) thyroid dermopathy (e.g., pretibial myxedema) occurs in 1–5% of Graves’ disease patients. Conclusion. Dermatologic evaluation can expedite endocrine diagnosis, particularly in resource-limited settings. Interdisciplinary collaboration is essential for optimal patient management

Keywords: endocrine dermatology, cutaneous markers, insulin resistance, hirsutism, thyroid dermopathy

First page

578

Last page

583

For citation:Khalimova Z.Y., Sabirov U.Y., Mirsaidova U.A. - ENDOCRINE DYSFUNCTIONS AND DERMATOLOGIC SIGNS: EPIDEMIOLOGY AND DIFFERENTIAL DIAGNOSIS//New Day in Medicine 6(80)2025 578-583 https://newdayworldmedicine.com/en/new_day_medicine/6-80-2025

List of References

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