134 -6 (80) 2025 - Naimov F.F., Makhmudova L.I. - CLINICAL SIGNIFICANCE OF BIOMARKERS OF DISORDERS OF ACID-BASE COMPOSITION AND BLOOD HEMOSTASIS IN CORONARY ARTERY DISEASE WITH COMORBID CONDITIONS

CLINICAL SIGNIFICANCE OF BIOMARKERS OF DISORDERS OF ACID-BASE COMPOSITION AND BLOOD HEMOSTASIS IN CORONARY ARTERY DISEASE WITH COMORBID CONDITIONS

Naimov F.F. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Makhmudova L.I. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Resume

The article discusses the importance of biomarkers of the acid-base state (ASC) and the hemostasis system in patients with coronary artery disease (CHD), aggravated by comorbid pathology, including hypertension, type 2 diabetes mellitus and obesity. Data on changes in the parameters of HCL (pH, PCO₂, hco₃⁻) and coagulation homeostasis (APTT, PTI, fibrinogen, D-dimer) are presented. It has been established that certain deviations of the CSCL and hemostasis biomarkers correlate with the severity of coronary heart disease and the severity of comorbidity, which allows them to be considered as potential prognostic markers

Key words: coronary heart disease, acid-base state, hemostasis, biomarkers, comorbidity, prognosis

First page

680

Last page

682

For citation:Naimov F.F., Makhmudova L.I. - CLINICAL SIGNIFICANCE OF BIOMARKERS OF DISORDERS OF ACID-BASE COMPOSITION AND BLOOD HEMOSTASIS IN CORONARY ARTERY DISEASE WITH COMORBID CONDITIONS//New Day in Medicine 6(80)2025 680-682 https://newdayworldmedicine.com/en/new_day_medicine/6-80-2025

List of References

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