170 -6 (80) 2025 - Pak U.I., Narzikulov R.M. - CLINICAL AND LABORATORY FEATURES OF CANDIDAL ESOPHAGITIS IN IMMUNODEFICIENT PATIENTS

CLINICAL AND LABORATORY FEATURES OF CANDIDAL ESOPHAGITIS IN IMMUNODEFICIENT PATIENTS

Pak U.I. - Samarkand regional branch of the Republican Specialized Dermatovenerological and Cosmetological Scientific and Practical Medical Center

Narzikulov R.M. - Samarkand State Medical University

Resume

Candidiasis esophagitis (CE) is a frequent opportunistic esophageal infection occurring predominantly in immunodeficient patients. The aim of the present study was to identify clinical and laboratory features of the course of CE in patients with various forms of secondary immunodeficiency (HIV infection, chemotherapy, transplantation, systemic diseases). The study included 72 patients with a verified diagnosis of candidal esophagitis. Clinical evaluation, esophagoscopy, mycologic examination and immune status analysis were performed. A direct correlation between the severity of immunodeficiency and the severity of clinical manifestations of CE was established. In patients with HIV infection the disease was characterized by a more severe course, extensive mucosal lesions and a high level of fungal load. The obtained data indicate the need for early diagnosis and individualized approach to the treatment of this pathology in patients with immunodeficiency

Keywords: candidal esophagitis, immunodeficiency, Candida albicans, HIV, esophagoscopy, mycoses, antimycotic therapy

First page

877

Last page

881

For citation:Pak U.I., Narzikulov R.M. - CLINICAL AND LABORATORY FEATURES OF CANDIDAL ESOPHAGITIS IN IMMUNODEFICIENT PATIENTS//New Day in Medicine 6(80)2025 877-881 https://newdayworldmedicine.com/en/new_day_medicine/6-80-2025

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