58 -7 (81) 2025 - Ashurova Sh.U., Kharibova E.A. - METHOD FOR DETERMINING MORPHOLOGICAL CHANGES IN THE RECTUM AS A RESULT OF CHEMOTHERAPY IN EXPERIMENTAL BREAST CANCER

METHOD FOR DETERMINING MORPHOLOGICAL CHANGES IN THE RECTUM AS A RESULT OF CHEMOTHERAPY IN EXPERIMENTAL BREAST CANCER

Ashurova Sh.U. - Bukhara State Medical Institute named after Abu Ali ibn Sina

Kharibova E.A. - Bukhara State Medical Institute named after Abu Ali ibn Sina

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According to the World Health Organization, cancer is a general term that encompasses a wide range of diseases that can affect any organ or system of the human body. The terms "benign tumors" and "malignant tumors" are also used to describe this category of diseases. One of the hallmarks of cancer is that it is characterized by the rapid proliferation of atypical cells, which can grow beyond their normal boundaries, invade surrounding tissues, and migrate to other organs, i.e.,metastasize. In a study of the small intestinal mucosa of mice, the height of the intestinal villi increased by 35% when following a high-calorie diet containing 10% fat (417 µm in the control group and 563 µm in the experimental group). A decrease in the number of absorptive areas per mm² in the rectum was observed in rats maintained on a diet with 32% fat content. Experimental models showed an enlargement of the intestinal cavity, which leads to the development of obesity. Standard nutrition over a period of 5 weeks (a diet with 14% fat content) showed signs of inflammation developing in the epithelium of the rectal mucosa

Keywords: breast cancer, rectum, morphology, chemotherapy

First page

296

Last page

302

For citation:Ashurova Sh.U., Kharibova E.A. - METHOD FOR DETERMINING MORPHOLOGICAL CHANGES IN THE RECTUM AS A RESULT OF CHEMOTHERAPY IN EXPERIMENTAL BREAST CANCER//New Day in Medicine 7(81)2025 296-302 https://newdayworldmedicine.com/en/new_day_medicine/7-81-2025

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